Tue, 21 Mar 2023

IgBLAST 1.21.0 is now available!

The improvements in this latest version are available to both the command line and web IgBLAST users.


  • Added gaps to all _alignments_aa fields (such as sequence_alignment_aa) to reflect gaps in nucleotide sequence alignment.

  • Added the new AIRR format field: sequence_aa. This is the direct translation (no gaps) of a nucleotide sequence using the reading frame determined by the nucleotide alignment to its closest germline V gene.

  • Added the new AIRR format field: d_frame. This is the D gene frame that is in-frame with the J gene coding frame. IgBLAST offers built-in IGHD gene frame support for mouse as defined by Ichihara Y et al (European Journal of Immunology Volume 19, Issue 10 p. 1849-1854). Users can use their own custom D gene definition with IgBLAST depending on their needs.

Download IgBLAST here https://ftp.ncbi.nih.gov/blast/executables/igblast/release/LATEST.

Checkout the IgBLAST GitHub page at https://ncbi.github.io/igblast/.

Mon, 09 Jan 2023

ElasticBLAST 1.0.0 is Now available!

ElasticBLAST version 1.0.0 has support for faster cheaper disks at AWS and better supports Kubernetes on GCP!

ElasticBLAST versions prior to version 1.0.0 will stop working on GCP after January 31, 2023.

This is because older versions of ElasticBLAST rely on version 1.21 of kubernetes, which will reach its end of life on the Google Kubernetes Engine on that date. Please upgrade your installation of ElasticBLAST to its latest version.


Bug fixes

  • ElasticBLAST uses GCP’s recommended way of dealing with read/write persistent disk.

  • Long user names no longer cause errors in AWS.

  • Fixed error caused by APIs not being enabled in GCP.

Please checkout this bioRxiv paper: ElasticBLAST: Accelerating Sequence Search via Cloud Computing.