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Summary [?]

A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query: EAW86454.1 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), isoform CRA_c [Homo sapiens] >dbj|BAG59399.1| unnamed protein product [Homo sapiens] ... Query length: 204 aa
uncharacterized protein LOC553452 [Danio rerio] >gb|AAI24752.1| Si:dkey-180p18.9 [Danio rerio] ...
uncharacterized protein LOC553452 [Danio rerio] >gb|AAI16546.2| Si:dkey-180p18.9 [Danio rerio] >gb|AAI24752.1| Si:dkey-180p18.9 [Danio rerio]
316 aa protein
accession:NP_001070715.1
estradiol 17 beta-dehydrogenase 5 isoform 1 eta-dehydrogenase 5; AltName: Full=17-beta-HSD 5 [Mus musculus] >gb|AAD41250.1| type 5 17beta hydroxysteroid dehydrogenase [Mus musculus] >gb|AAH56643.1| Aldo-keto reductase family 1, member C6 [Mus musculus] >gb|EDL32249.1| mCG9091, isoform CRA_d [Mus musculus] >dbj|BAA08285.1| estradiol 17-beta-dehydrogenase [Mus musculus] >dbj|BAE28891.1| unnamed protein product [Mus musculus] ...
estradiol 17 beta-dehydrogenase 5 isoform 1 [Mus musculus] >sp|P70694.1| RecName: Full=Estradiol 17 beta-dehydrogenase 5; AltName: Full=17-beta-HSD 5 [Mus musculus] >gb|AAD41250.1| type 5 17beta hydroxysteroid dehydrogenase [Mus musculus] >gb|AAH56643.1| Aldo-keto reductase family 1, member C6 [Mus musculus] >gb|EDL32249.1| mCG9091, isoform CRA_d [Mus musculus] >dbj|BAA08285.1| estradiol 17-beta-dehydrogenase [Mus musculus] >dbj|BAE28891.1| unnamed protein product [Mus musculus]
323 aa protein
accession:NP_085114.1
aldo-keto reductase family 1 member C1 reductase family 1 member C1; AltName: Full=20-alpha-hydroxysteroid dehydrogenase; Short=20-alpha-HSD; AltName: Full=Chlordecone reductase homolog HAKRC; AltName: Full=Dihydrodiol dehydrogenase 1; Short=DD1; AltName: Full=High-affinity hepatic bile acid-binding protein; Short=HBAB [Homo sapiens] >pdb|3C3U|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|3NTY|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|4YVP|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|4YVP|B Chain B, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|6IJX|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >gb|AAX31897.1| aldo-keto reductase family 1 member C1 [synthetic construct] >emb|SJX35118.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAA16227.1| dihydrodiol dehydrogenase [Homo sapiens] >gb|AAA18115.1| hepatic dihydrodiol dehydrogenase [Homo sapiens] >gb|AAB02880.1| dihydrodiol dehydrogenase [Homo sapiens] ...
aldo-keto reductase family 1 member C1 [Homo sapiens] >sp|Q04828.1| RecName: Full=Aldo-keto reductase family 1 member C1; AltName: Full=20-alpha-hydroxysteroid dehydrogenase; Short=20-alpha-HSD; AltName: Full=Chlordecone reductase homolog HAKRC; AltName: Full=Dihydrodiol dehydrogenase 1; Short=DD1; AltName: Full=High-affinity hepatic bile acid-binding protein; Short=HBAB [Homo sapiens] >pdb|3C3U|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|3NTY|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|4YVP|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|4YVP|B Chain B, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|6IJX|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >gb|AAX31897.1| aldo-keto reductase family 1 member C1 [synthetic construct] >emb|SJX35118.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAA16227.1| dihydrodiol dehydrogenase [Homo sapiens] >gb|AAA18115.1| hepatic dihydrodiol dehydrogenase [Homo sapiens] >gb|AAB02880.1| dihydrodiol dehydrogenase [Homo sapiens]
323 aa protein
accession:NP_001344.2
aldo-keto reductase family 1 member C3 isoform 1 family 1 member C3; AltName: Full=17-beta-hydroxysteroid dehydrogenase type 5; Short=17-beta-HSD 5; AltName: Full=3-alpha-HSD type II, brain; AltName: Full=3-alpha-hydroxysteroid dehydrogenase type 2; Short=3-alpha-HSD type 2; AltName: Full=Chlordecone reductase homolog HAKRb; AltName: Full=Dihydrodiol dehydrogenase 3; Short=DD-3; Short=DD3; AltName: Full=Dihydrodiol dehydrogenase type I; AltName: Full=HA1753; AltName: Full=Prostaglandin F synthase; Short=PGFS; AltName: Full=Testosterone 17-beta-dehydrogenase 5 [Homo sapiens] >pdb|4YVV|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVV|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVX|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVX|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4ZFC|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4ZFC|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|6A7B|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|6A7B|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|8RB6|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|8RB6|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >gb|AAX42121.1| aldo-keto reductase family 1 member C3 [synthetic construct] >emb|SJX35022.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAH01479.1| Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens] >gb|AAH19230.1| Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens] >gb|AAP35950.1| aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens] ...
aldo-keto reductase family 1 member C3 isoform 1 [Homo sapiens] >sp|P42330.4| RecName: Full=Aldo-keto reductase family 1 member C3; AltName: Full=17-beta-hydroxysteroid dehydrogenase type 5; Short=17-beta-HSD 5; AltName: Full=3-alpha-HSD type II, brain; AltName: Full=3-alpha-hydroxysteroid dehydrogenase type 2; Short=3-alpha-HSD type 2; AltName: Full=Chlordecone reductase homolog HAKRb; AltName: Full=Dihydrodiol dehydrogenase 3; Short=DD-3; Short=DD3; AltName: Full=Dihydrodiol dehydrogenase type I; AltName: Full=HA1753; AltName: Full=Prostaglandin F synthase; Short=PGFS; AltName: Full=Testosterone 17-beta-dehydrogenase 5 [Homo sapiens] >pdb|4YVV|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVV|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVX|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVX|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4ZFC|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4ZFC|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|6A7B|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|6A7B|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|8RB6|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|8RB6|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >gb|AAX42121.1| aldo-keto reductase family 1 member C3 [synthetic construct] >emb|SJX35022.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAH01479.1| Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens] >gb|AAH19230.1| Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens] >gb|AAP35950.1| aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens]
323 aa protein
accession:NP_003730.4
Query: aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), isoform CRA_c ...
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), isoform CRA_c [Homo sapiens] >dbj|BAG59399.1| unnamed protein product [Homo sapiens]
204 aa protein
accession:EAW86454.1
aldo-keto reductase family 1 member C3 isoform 2 member C3 [Homo sapiens] >gb|KAI4075081.1| aldo-keto reductase family 1 member C3 [Homo sapiens] ...
aldo-keto reductase family 1 member C3 isoform 2 [Homo sapiens] >gb|KAI2554896.1| aldo-keto reductase family 1 member C3 [Homo sapiens] >gb|KAI4075081.1| aldo-keto reductase family 1 member C3 [Homo sapiens]
323 aa protein
accession:NP_001240837.1

Descriptions

Best hits

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Alignments Download
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Best hits producing significant alignments
Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession
1
aldo-keto reductase family 1 member C3 isoform 2 [Homo sapiens] >gb|KAI2554896.1| aldo-keto reductase family 1 member C3 [Homo sapiens] >gb|KAI4075081.1| aldo-keto reductase family 1 member C3 [Homo sapiens]
428 428 100% 2e-152100.00% NP_001240837.1
2
estradiol 17 beta-dehydrogenase 5 isoform 1 [Mus musculus] >sp|P70694.1| RecName: Full=Estradiol 17 beta-dehydrogenase 5; AltName: Full=17-beta-HSD 5 [Mus musculus] >gb|AAD41250.1| type 5 17beta hydroxysteroid dehydrogenase [Mus musculus] >gb|AAH56643.1| Aldo-keto reductase family 1, member C6 [Mus musculus] >gb|EDL32249.1| mCG9091, isoform CRA_d [Mus musculus] >dbj|BAA08285.1| estradiol 17-beta-dehydrogenase [Mus musculus] >dbj|BAE28891.1| unnamed protein product [Mus musculus]
332 332 100% 3e-11474.02% NP_085114.1
3
uncharacterized protein LOC553452 [Danio rerio] >gb|AAI16546.2| Si:dkey-180p18.9 [Danio rerio] >gb|AAI24752.1| Si:dkey-180p18.9 [Danio rerio]
214 214 100% 2e-6850.49% NP_001070715.1
4
aldo-keto reductase family 1 member C3 isoform 1 [Homo sapiens] >sp|P42330.4| RecName: Full=Aldo-keto reductase family 1 member C3; AltName: Full=17-beta-hydroxysteroid dehydrogenase type 5; Short=17-beta-HSD 5; AltName: Full=3-alpha-HSD type II, brain; AltName: Full=3-alpha-hydroxysteroid dehydrogenase type 2; Short=3-alpha-HSD type 2; AltName: Full=Chlordecone reductase homolog HAKRb; AltName: Full=Dihydrodiol dehydrogenase 3; Short=DD-3; Short=DD3; AltName: Full=Dihydrodiol dehydrogenase type I; AltName: Full=HA1753; AltName: Full=Prostaglandin F synthase; Short=PGFS; AltName: Full=Testosterone 17-beta-dehydrogenase 5 [Homo sapiens] >pdb|4YVV|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVV|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVX|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4YVX|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4ZFC|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|4ZFC|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|6A7B|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|6A7B|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|8RB6|A Chain A, Aldo-keto reductase family 1 member C3 [Homo sapiens] >pdb|8RB6|B Chain B, Aldo-keto reductase family 1 member C3 [Homo sapiens] >gb|AAX42121.1| aldo-keto reductase family 1 member C3 [synthetic construct] >emb|SJX35022.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAH01479.1| Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens] >gb|AAH19230.1| Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens] >gb|AAP35950.1| aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Homo sapiens]
427 427 100% 3e-152100.00% NP_003730.4
5
aldo-keto reductase family 1 member C1 [Homo sapiens] >sp|Q04828.1| RecName: Full=Aldo-keto reductase family 1 member C1; AltName: Full=20-alpha-hydroxysteroid dehydrogenase; Short=20-alpha-HSD; AltName: Full=Chlordecone reductase homolog HAKRC; AltName: Full=Dihydrodiol dehydrogenase 1; Short=DD1; AltName: Full=High-affinity hepatic bile acid-binding protein; Short=HBAB [Homo sapiens] >pdb|3C3U|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|3NTY|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|4YVP|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|4YVP|B Chain B, Aldo-keto reductase family 1 member C1 [Homo sapiens] >pdb|6IJX|A Chain A, Aldo-keto reductase family 1 member C1 [Homo sapiens] >gb|AAX31897.1| aldo-keto reductase family 1 member C1 [synthetic construct] >emb|SJX35118.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAA16227.1| dihydrodiol dehydrogenase [Homo sapiens] >gb|AAA18115.1| hepatic dihydrodiol dehydrogenase [Homo sapiens] >gb|AAB02880.1| dihydrodiol dehydrogenase [Homo sapiens]
374 374 100% 6e-13186.27% NP_001344.2