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Summary [?]

A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query: P49768.1 RecName: Full=Presenilin-1; Short=PS-1; AltName: Full=Protein S182; Contains: RecName: Full=Presenilin-1 NTF subunit; Contains: RecName: Full=Presenilin-1 CTF subunit; Contains: RecName: Full=Presenilin-1 CTF12; Short=PS1-CTF12 ... Query length: 467 aa
Presenilin sel-12 cName: Full=Presenilin sel-12; AltName: Full=Suppressor/enhancer of lin-12 protein 12 [Caenorhabditis elegans] >gb|AAD50991.1| presenilin SEL-12 [Caenorhabditis elegans] >emb|CCD70617.1| Presenilin sel-12 [Caenorhabditis elegans] ...
Presenilin sel-12 [Caenorhabditis elegans] >sp|P52166.2| RecName: Full=Presenilin sel-12; AltName: Full=Suppressor/enhancer of lin-12 protein 12 [Caenorhabditis elegans] >gb|AAD50991.1| presenilin SEL-12 [Caenorhabditis elegans] >emb|CCD70617.1| Presenilin sel-12 [Caenorhabditis elegans]
444 aa protein
accession:NP_508175.1
presenilin, isoform C enilin, isoform C [Drosophila melanogaster] ...
presenilin, isoform C [Drosophila melanogaster] >gb|ACL83343.1| presenilin, isoform C [Drosophila melanogaster]
508 aa protein
accession:NP_001137988.1
presenilin-1 isoform X2 ...
presenilin-1 isoform X2 [Danio rerio]
455 aa protein
accession:XP_005169940.1
presenilin-1 precursor : Full=Presenilin-1; Short=PS-1; AltName: Full=Protein S182; Contains: RecName: Full=Presenilin-1 NTF subunit; Contains: RecName: Full=Presenilin-1 CTF subunit; Contains: RecName: Full=Presenilin-1 CTF12; Short=PS1-CTF12 [Mus musculus] >gb|AAH71233.1| Psen1 protein [synthetic construct] >gb|AAB72049.1| presenilin-1 [Mus musculus] >gb|AAC42094.1| S182 protein [Mus musculus] >gb|AAH30409.1| Psen1 protein [Mus musculus] >gb|EDL02742.1| presenilin 1, isoform CRA_a [Mus musculus] ...
presenilin-1 precursor [Mus musculus] >sp|P49769.1| RecName: Full=Presenilin-1; Short=PS-1; AltName: Full=Protein S182; Contains: RecName: Full=Presenilin-1 NTF subunit; Contains: RecName: Full=Presenilin-1 CTF subunit; Contains: RecName: Full=Presenilin-1 CTF12; Short=PS1-CTF12 [Mus musculus] >gb|AAH71233.1| Psen1 protein [synthetic construct] >gb|AAB72049.1| presenilin-1 [Mus musculus] >gb|AAC42094.1| S182 protein [Mus musculus] >gb|AAH30409.1| Psen1 protein [Mus musculus] >gb|EDL02742.1| presenilin 1, isoform CRA_a [Mus musculus]
467 aa protein
accession:NP_001349200.1
Query: RecName: Full=Presenilin-1; Short=PS-1; AltName: Full=Protein S182; Contains: RecName: Full=Presenilin-1 NTF subunit; Contains: RecName: Full=Presenilin-1 CTF subunit; Contains: RecName: Full=Presenilin-1 CTF12; Short=PS1-CTF12 ...
RecName: Full=Presenilin-1; Short=PS-1; AltName: Full=Protein S182; Contains: RecName: Full=Presenilin-1 NTF subunit; Contains: RecName: Full=Presenilin-1 CTF subunit; Contains: RecName: Full=Presenilin-1 CTF12; Short=PS1-CTF12
467 aa protein
accession:P49768.1
presenilin-1 isoform I-463 enilin-1 isoform X2 [Homo sapiens] >ref|XP_005561763.1| presenilin-1 isoform X2 [Macaca fascicularis] >ref|XP_008976108.1| presenilin-1 isoform X2 [Pan paniscus] >ref|XP_011535275.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_011535276.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_011760895.1| presenilin-1 isoform X2 [Macaca nemestrina] >ref|XP_011805007.1| PREDICTED: presenilin-1 isoform X2 [Colobus angolensis palliatus] >ref|XP_011805008.1| PREDICTED: presenilin-1 isoform X2 [Colobus angolensis palliatus] >ref|XP_011838491.1| PREDICTED: presenilin-1 isoform X2 [Mandrillus leucophaeus] >ref|XP_011838493.1| PREDICTED: presenilin-1 isoform X2 [Mandrillus leucophaeus] >ref|XP_011945274.1| PREDICTED: presenilin-1 isoform X2 [Cercocebus atys] >ref|XP_012359857.1| presenilin-1 isoform X2 [Nomascus leucogenys] >ref|XP_014999523.1| presenilin-1 isoform X2 [Macaca mulatta] >ref|XP_016781832.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781833.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781835.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781836.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_023038952.1| presenilin-1 isoform X2 [Piliocolobus tephrosceles] >ref|XP_023038961.1| presenilin-1 isoform X2 [Piliocolobus tephrosceles] >ref|XP_025247288.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_025247290.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_025247291.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_028706047.1| presenilin-1 isoform X2 [Macaca mulatta] >ref|XP_030668896.1| presenilin-1 isoform X2 [Nomascus leucogenys] >ref|XP_031523869.1| presenilin-1 isoform X2 [Papio anubis] >ref|XP_047287558.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_050654787.1| presenilin-1 isoform X2 [Macaca thibetana thibetana] >ref|XP_054232392.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232393.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232394.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232395.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_055144881.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063500364.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063500366.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063649723.1| presenilin-1 isoform X3 [Pan troglodytes] >gb|ADQ31747.1| presenilin 1 (Alzheimer disease 3), partial [synthetic construct] >emb|SJX48674.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAB05894.1| presenilin I-463 [Homo sapiens] >gb|AAH11729.1| PSEN1 protein [Homo sapiens] >gb|AIC49497.1| PSEN1, partial [synthetic construct] ...
presenilin-1 isoform I-463 [Homo sapiens] >ref|XP_005267923.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_005561763.1| presenilin-1 isoform X2 [Macaca fascicularis] >ref|XP_008976108.1| presenilin-1 isoform X2 [Pan paniscus] >ref|XP_011535275.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_011535276.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_011760895.1| presenilin-1 isoform X2 [Macaca nemestrina] >ref|XP_011805007.1| PREDICTED: presenilin-1 isoform X2 [Colobus angolensis palliatus] >ref|XP_011805008.1| PREDICTED: presenilin-1 isoform X2 [Colobus angolensis palliatus] >ref|XP_011838491.1| PREDICTED: presenilin-1 isoform X2 [Mandrillus leucophaeus] >ref|XP_011838493.1| PREDICTED: presenilin-1 isoform X2 [Mandrillus leucophaeus] >ref|XP_011945274.1| PREDICTED: presenilin-1 isoform X2 [Cercocebus atys] >ref|XP_012359857.1| presenilin-1 isoform X2 [Nomascus leucogenys] >ref|XP_014999523.1| presenilin-1 isoform X2 [Macaca mulatta] >ref|XP_016781832.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781833.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781835.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781836.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_023038952.1| presenilin-1 isoform X2 [Piliocolobus tephrosceles] >ref|XP_023038961.1| presenilin-1 isoform X2 [Piliocolobus tephrosceles] >ref|XP_025247288.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_025247290.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_025247291.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_028706047.1| presenilin-1 isoform X2 [Macaca mulatta] >ref|XP_030668896.1| presenilin-1 isoform X2 [Nomascus leucogenys] >ref|XP_031523869.1| presenilin-1 isoform X2 [Papio anubis] >ref|XP_047287558.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_050654787.1| presenilin-1 isoform X2 [Macaca thibetana thibetana] >ref|XP_054232392.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232393.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232394.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232395.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_055144881.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063500364.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063500366.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063649723.1| presenilin-1 isoform X3 [Pan troglodytes] >gb|ADQ31747.1| presenilin 1 (Alzheimer disease 3), partial [synthetic construct] >emb|SJX48674.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAB05894.1| presenilin I-463 [Homo sapiens] >gb|AAH11729.1| PSEN1 protein [Homo sapiens] >gb|AIC49497.1| PSEN1, partial [synthetic construct]
463 aa protein
accession:NP_015557.2

Descriptions

Best hits

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Best hits producing significant alignments
Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession
1
presenilin-1 isoform I-463 [Homo sapiens] >ref|XP_005267923.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_005561763.1| presenilin-1 isoform X2 [Macaca fascicularis] >ref|XP_008976108.1| presenilin-1 isoform X2 [Pan paniscus] >ref|XP_011535275.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_011535276.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_011760895.1| presenilin-1 isoform X2 [Macaca nemestrina] >ref|XP_011805007.1| PREDICTED: presenilin-1 isoform X2 [Colobus angolensis palliatus] >ref|XP_011805008.1| PREDICTED: presenilin-1 isoform X2 [Colobus angolensis palliatus] >ref|XP_011838491.1| PREDICTED: presenilin-1 isoform X2 [Mandrillus leucophaeus] >ref|XP_011838493.1| PREDICTED: presenilin-1 isoform X2 [Mandrillus leucophaeus] >ref|XP_011945274.1| PREDICTED: presenilin-1 isoform X2 [Cercocebus atys] >ref|XP_012359857.1| presenilin-1 isoform X2 [Nomascus leucogenys] >ref|XP_014999523.1| presenilin-1 isoform X2 [Macaca mulatta] >ref|XP_016781832.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781833.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781835.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_016781836.1| presenilin-1 isoform X3 [Pan troglodytes] >ref|XP_023038952.1| presenilin-1 isoform X2 [Piliocolobus tephrosceles] >ref|XP_023038961.1| presenilin-1 isoform X2 [Piliocolobus tephrosceles] >ref|XP_025247288.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_025247290.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_025247291.1| presenilin-1 isoform X2 [Theropithecus gelada] >ref|XP_028706047.1| presenilin-1 isoform X2 [Macaca mulatta] >ref|XP_030668896.1| presenilin-1 isoform X2 [Nomascus leucogenys] >ref|XP_031523869.1| presenilin-1 isoform X2 [Papio anubis] >ref|XP_047287558.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_050654787.1| presenilin-1 isoform X2 [Macaca thibetana thibetana] >ref|XP_054232392.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232393.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232394.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_054232395.1| presenilin-1 isoform X2 [Homo sapiens] >ref|XP_055144881.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063500364.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063500366.1| presenilin-1 isoform X1 [Symphalangus syndactylus] >ref|XP_063649723.1| presenilin-1 isoform X3 [Pan troglodytes] >gb|ADQ31747.1| presenilin 1 (Alzheimer disease 3), partial [synthetic construct] >emb|SJX48674.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAB05894.1| presenilin I-463 [Homo sapiens] >gb|AAH11729.1| PSEN1 protein [Homo sapiens] >gb|AIC49497.1| PSEN1, partial [synthetic construct]
952 952 100% 0.099.14% NP_015557.2
2
presenilin-1 precursor [Mus musculus] >sp|P49769.1| RecName: Full=Presenilin-1; Short=PS-1; AltName: Full=Protein S182; Contains: RecName: Full=Presenilin-1 NTF subunit; Contains: RecName: Full=Presenilin-1 CTF subunit; Contains: RecName: Full=Presenilin-1 CTF12; Short=PS1-CTF12 [Mus musculus] >gb|AAH71233.1| Psen1 protein [synthetic construct] >gb|AAB72049.1| presenilin-1 [Mus musculus] >gb|AAC42094.1| S182 protein [Mus musculus] >gb|AAH30409.1| Psen1 protein [Mus musculus] >gb|EDL02742.1| presenilin 1, isoform CRA_a [Mus musculus]
811 811 100% 0.092.72% NP_001349200.1
3
presenilin-1 isoform X2 [Danio rerio]
555 555 97% 0.071.96% XP_005169940.1
4
presenilin, isoform C [Drosophila melanogaster] >gb|ACL83343.1| presenilin, isoform C [Drosophila melanogaster]
424 424 85% 8e-14455.66% NP_001137988.1
5
Presenilin sel-12 [Caenorhabditis elegans] >sp|P52166.2| RecName: Full=Presenilin sel-12; AltName: Full=Suppressor/enhancer of lin-12 protein 12 [Caenorhabditis elegans] >gb|AAD50991.1| presenilin SEL-12 [Caenorhabditis elegans] >emb|CCD70617.1| Presenilin sel-12 [Caenorhabditis elegans]
417 417 92% 7e-14249.66% NP_508175.1