Summary [?]
A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query:
NP_524182.3
insulin degrading metalloproteinase [Drosophila melanogaster] >sp|P22817.4| RecName: Full=Insulin-degrading enzyme; AltName: Full=Insulin protease; Short=Insulinase; AltName: Full=Insulysin [Drosophila melanogaster] >gb|AAF51584.3| insulin degrading metalloproteinase [Drosophila melanogaster]
...
Query length:
990 aa
DOMAINS: and other(s) domains
...
metalloendopeptidase me: Full=A-factor-processing enzyme; AltName: Full=Insulin-degrading enzyme homolog [Saccharomyces cerevisiae S288C] >gb|AAB82351.2| Ste23p [Saccharomyces cerevisiae] >gb|AJV52701.1| Ste23p [Saccharomyces cerevisiae YJM1307] >gb|AJV57199.1| Ste23p [Saccharomyces cerevisiae YJM1381] >gb|WNV73101.1| STE23 [Saccharomyces cerevisiae synthetic construct] >gb|KAF1904934.1| metalloendopeptidase, partial [Saccharomyces cerevisiae]
...
metalloendopeptidase [Saccharomyces cerevisiae S288C] >sp|Q06010.2| RecName: Full=A-factor-processing enzyme; AltName: Full=Insulin-degrading enzyme homolog [Saccharomyces cerevisiae S288C] >gb|AAB82351.2| Ste23p [Saccharomyces cerevisiae] >gb|AJV52701.1| Ste23p [Saccharomyces cerevisiae YJM1307] >gb|AJV57199.1| Ste23p [Saccharomyces cerevisiae YJM1381] >gb|WNV73101.1| STE23 [Saccharomyces cerevisiae synthetic construct] >gb|KAF1904934.1| metalloendopeptidase, partial [Saccharomyces cerevisiae]
1027 aa protein
accession:NP_013493.2
insulin-degrading enzyme isoform X1 ilar to H.sapiens IDE, insulin-degrading enzyme (IDE, zgc:162603) [Danio rerio]
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insulin-degrading enzyme isoform X1 [Danio rerio] >emb|CAX13065.1| novel protein similar to H.sapiens IDE, insulin-degrading enzyme (IDE, zgc:162603) [Danio rerio]
998 aa protein
accession:XP_005169584.1
insulin-degrading enzyme isoform 1 in-degrading enzyme; AltName: Full=Abeta-degrading protease; AltName: Full=Insulin protease; Short=Insulinase; AltName: Full=Insulysin [Homo sapiens] >gb|AIC49009.1| IDE, partial [synthetic construct] >emb|SJX26104.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAH96336.1| Insulin-degrading enzyme [Homo sapiens] >gb|AAH96337.1| Insulin-degrading enzyme [Homo sapiens] >gb|AAH96339.1| Insulin-degrading enzyme [Homo sapiens]
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insulin-degrading enzyme isoform 1 [Homo sapiens] >sp|P14735.4| RecName: Full=Insulin-degrading enzyme; AltName: Full=Abeta-degrading protease; AltName: Full=Insulin protease; Short=Insulinase; AltName: Full=Insulysin [Homo sapiens] >gb|AIC49009.1| IDE, partial [synthetic construct] >emb|SJX26104.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAH96336.1| Insulin-degrading enzyme [Homo sapiens] >gb|AAH96337.1| Insulin-degrading enzyme [Homo sapiens] >gb|AAH96339.1| Insulin-degrading enzyme [Homo sapiens]
1019 aa protein
accession:NP_004960.2
insulin-degrading enzyme degrading enzyme [Mus musculus]
...
insulin-degrading enzyme [Mus musculus] >gb|AAH41675.1| Insulin degrading enzyme [Mus musculus]
1019 aa protein
accession:NP_112419.4
Query: insulin degrading metalloproteinase n-degrading enzyme; AltName: Full=Insulin protease; Short=Insulinase; AltName: Full=Insulysin [Drosophila melanogaster] >gb|AAF51584.3| insulin degrading metalloproteinase [Drosophila melanogaster]
...
insulin degrading metalloproteinase [Drosophila melanogaster] >sp|P22817.4| RecName: Full=Insulin-degrading enzyme; AltName: Full=Insulin protease; Short=Insulinase; AltName: Full=Insulysin [Drosophila melanogaster] >gb|AAF51584.3| insulin degrading metalloproteinase [Drosophila melanogaster]
990 aa protein
accession:NP_524182.3
Insulin-degrading enzyme n-degrading enzyme [Caenorhabditis elegans]
...
Insulin-degrading enzyme [Caenorhabditis elegans] >emb|CCD67861.1| Insulin-degrading enzyme [Caenorhabditis elegans]
1051 aa protein
accession:NP_741542.1
DOMAINS: and other(s) domains
...
metalloendopeptidase [Saccharomyces cerevisiae S288C] >sp|Q06010.2| RecName: Full=A-factor-processing enzyme; AltName: Full=Insulin-degrading enzyme homolog [Saccharomyces cerevisiae S288C] >gb|AAB82351.2| Ste23p [Saccharomyces cerevisiae] >gb|AJV52701.1| Ste23p [Saccharomyces cerevisiae YJM1307] >gb|AJV57199.1| Ste23p [Saccharomyces cerevisiae YJM1381] >gb|WNV73101.1| STE23 [Saccharomyces cerevisiae synthetic construct] >gb|KAF1904934.1| metalloendopeptidase, partial [Saccharomyces cerevisiae]
1027 aa protein
accession:NP_013493.2
insulin-degrading enzyme isoform X1 [Danio rerio] >emb|CAX13065.1| novel protein similar to H.sapiens IDE, insulin-degrading enzyme (IDE, zgc:162603) [Danio rerio]
998 aa protein
accession:XP_005169584.1
insulin-degrading enzyme isoform 1 [Homo sapiens] >sp|P14735.4| RecName: Full=Insulin-degrading enzyme; AltName: Full=Abeta-degrading protease; AltName: Full=Insulin protease; Short=Insulinase; AltName: Full=Insulysin [Homo sapiens] >gb|AIC49009.1| IDE, partial [synthetic construct] >emb|SJX26104.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAH96336.1| Insulin-degrading enzyme [Homo sapiens] >gb|AAH96337.1| Insulin-degrading enzyme [Homo sapiens] >gb|AAH96339.1| Insulin-degrading enzyme [Homo sapiens]
1019 aa protein
accession:NP_004960.2
insulin-degrading enzyme [Mus musculus] >gb|AAH41675.1| Insulin degrading enzyme [Mus musculus]
1019 aa protein
accession:NP_112419.4
insulin degrading metalloproteinase [Drosophila melanogaster] >sp|P22817.4| RecName: Full=Insulin-degrading enzyme; AltName: Full=Insulin protease; Short=Insulinase; AltName: Full=Insulysin [Drosophila melanogaster] >gb|AAF51584.3| insulin degrading metalloproteinase [Drosophila melanogaster]
990 aa protein
accession:NP_524182.3
Insulin-degrading enzyme [Caenorhabditis elegans] >emb|CCD67861.1| Insulin-degrading enzyme [Caenorhabditis elegans]
1051 aa protein
accession:NP_741542.1
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Legend
Query sequence
nr matches
Landmark matches
Not aligned to query
Gap
Descriptions
Best hits
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Alignments
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Distance tree of results
Multiple alignment
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Available columns
Select for downloading or viewing reports | Description | Max score | Total score | Query cover | E value | Ident | Accession |
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1 | 948 | 948 | 96% | 0.0 | 46.54% | XP_005169584.1 | |
2 | 936 | 936 | 96% | 0.0 | 46.69% | NP_004960.2 | |
3 | 934 | 934 | 96% | 0.0 | 46.69% | NP_112419.4 | |
4 | 760 | 760 | 93% | 0.0 | 41.73% | NP_741542.1 | |
5 | 659 | 659 | 95% | 0.0 | 36.02% | NP_013493.2 |