Summary [?]
A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query:
NP_034700.2
insulin receptor substrate 1 [Mus musculus] >gb|AAI56077.1| Insulin receptor substrate 1, partial [synthetic construct] >gb|AAI57090.1| Insulin receptor substrate 1 [synthetic construct] >gb|EDL02131.1| insulin receptor substrate 1 [Mus musculus] >emb|CAA49378.1| insulin receptor substrate 1 [Mus musculus] >dbj|BAC32308.1| unnamed protein product [Mus musculus]
...
Query length:
1231 aa
DOMAINS: and other(s) domains
...
chico, isoform B 16.1| chico, isoform C [Drosophila melanogaster] >ref|NP_723540.1| chico, isoform A [Drosophila melanogaster] >sp|Q9XTN2.1| RecName: Full=Insulin receptor substrate 1; Short=dIRS; AltName: Full=Protein chico [Drosophila melanogaster] >gb|AOQ03587.1| chico-RA, partial [synthetic construct] >gb|AAD40880.1| insulin receptor substrate [Drosophila melanogaster] >gb|AAD43005.1| insulin receptor substrate [Drosophila melanogaster] >gb|AAF52882.1| chico, isoform A [Drosophila melanogaster] >gb|AAV37022.1| GH02661p [Drosophila melanogaster]
...
chico, isoform B [Drosophila melanogaster] >ref|NP_001260316.1| chico, isoform C [Drosophila melanogaster] >ref|NP_723540.1| chico, isoform A [Drosophila melanogaster] >sp|Q9XTN2.1| RecName: Full=Insulin receptor substrate 1; Short=dIRS; AltName: Full=Protein chico [Drosophila melanogaster] >gb|AOQ03587.1| chico-RA, partial [synthetic construct] >gb|AAD40880.1| insulin receptor substrate [Drosophila melanogaster] >gb|AAD43005.1| insulin receptor substrate [Drosophila melanogaster] >gb|AAF52882.1| chico, isoform A [Drosophila melanogaster] >gb|AAV37022.1| GH02661p [Drosophila melanogaster]
968 aa protein
accession:NP_001188772.1
insulin receptor substrate 2 =Insulin receptor substrate 2; Short=IRS-2; AltName: Full=4PS [Mus musculus] >gb|AAI47581.1| Insulin receptor substrate 2 [Mus musculus]
...
insulin receptor substrate 2 [Mus musculus] >sp|P81122.2| RecName: Full=Insulin receptor substrate 2; Short=IRS-2; AltName: Full=4PS [Mus musculus] >gb|AAI47581.1| Insulin receptor substrate 2 [Mus musculus]
1321 aa protein
accession:NP_001074681.1
insulin receptor substrate 2
...
insulin receptor substrate 2 [Danio rerio]
1062 aa protein
accession:XP_700746.4
insulin receptor substrate 1
...
insulin receptor substrate 1 [Danio rerio]
1099 aa protein
accession:XP_687702.4
Query: insulin receptor substrate 1 eptor substrate 1, partial [synthetic construct] >gb|AAI57090.1| Insulin receptor substrate 1 [synthetic construct] >gb|EDL02131.1| insulin receptor substrate 1 [Mus musculus] >emb|CAA49378.1| insulin receptor substrate 1 [Mus musculus] >dbj|BAC32308.1| unnamed protein product [Mus musculus]
...
insulin receptor substrate 1 [Mus musculus] >gb|AAI56077.1| Insulin receptor substrate 1, partial [synthetic construct] >gb|AAI57090.1| Insulin receptor substrate 1 [synthetic construct] >gb|EDL02131.1| insulin receptor substrate 1 [Mus musculus] >emb|CAA49378.1| insulin receptor substrate 1 [Mus musculus] >dbj|BAC32308.1| unnamed protein product [Mus musculus]
1231 aa protein
accession:NP_034700.2
insulin receptor substrate 1 n receptor substrate 1 isoform X1 [Homo sapiens] >ref|XP_047300180.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >ref|XP_054197850.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >sp|P35568.1| RecName: Full=Insulin receptor substrate 1; Short=IRS-1 [Homo sapiens] >gb|ACE86532.1| insulin receptor substrate 1 protein, partial [synthetic construct] >emb|SJX44554.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAB27175.1| insulin receptor substrate-1 [Homo sapiens] >gb|AAH53895.1| Insulin receptor substrate 1 [Homo sapiens] >gb|AIC49075.1| IRS1, partial [synthetic construct]
...
insulin receptor substrate 1 [Homo sapiens] >ref|XP_047300179.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >ref|XP_047300180.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >ref|XP_054197850.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >sp|P35568.1| RecName: Full=Insulin receptor substrate 1; Short=IRS-1 [Homo sapiens] >gb|ACE86532.1| insulin receptor substrate 1 protein, partial [synthetic construct] >emb|SJX44554.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAB27175.1| insulin receptor substrate-1 [Homo sapiens] >gb|AAH53895.1| Insulin receptor substrate 1 [Homo sapiens] >gb|AIC49075.1| IRS1, partial [synthetic construct]
1242 aa protein
accession:NP_005535.1
DOMAINS: and other(s) domains
...
chico, isoform B [Drosophila melanogaster] >ref|NP_001260316.1| chico, isoform C [Drosophila melanogaster] >ref|NP_723540.1| chico, isoform A [Drosophila melanogaster] >sp|Q9XTN2.1| RecName: Full=Insulin receptor substrate 1; Short=dIRS; AltName: Full=Protein chico [Drosophila melanogaster] >gb|AOQ03587.1| chico-RA, partial [synthetic construct] >gb|AAD40880.1| insulin receptor substrate [Drosophila melanogaster] >gb|AAD43005.1| insulin receptor substrate [Drosophila melanogaster] >gb|AAF52882.1| chico, isoform A [Drosophila melanogaster] >gb|AAV37022.1| GH02661p [Drosophila melanogaster]
968 aa protein
accession:NP_001188772.1
insulin receptor substrate 2 [Mus musculus] >sp|P81122.2| RecName: Full=Insulin receptor substrate 2; Short=IRS-2; AltName: Full=4PS [Mus musculus] >gb|AAI47581.1| Insulin receptor substrate 2 [Mus musculus]
1321 aa protein
accession:NP_001074681.1
insulin receptor substrate 2 [Danio rerio]
1062 aa protein
accession:XP_700746.4
insulin receptor substrate 1 [Danio rerio]
1099 aa protein
accession:XP_687702.4
insulin receptor substrate 1 [Mus musculus] >gb|AAI56077.1| Insulin receptor substrate 1, partial [synthetic construct] >gb|AAI57090.1| Insulin receptor substrate 1 [synthetic construct] >gb|EDL02131.1| insulin receptor substrate 1 [Mus musculus] >emb|CAA49378.1| insulin receptor substrate 1 [Mus musculus] >dbj|BAC32308.1| unnamed protein product [Mus musculus]
1231 aa protein
accession:NP_034700.2
insulin receptor substrate 1 [Homo sapiens] >ref|XP_047300179.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >ref|XP_047300180.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >ref|XP_054197850.1| insulin receptor substrate 1 isoform X1 [Homo sapiens] >sp|P35568.1| RecName: Full=Insulin receptor substrate 1; Short=IRS-1 [Homo sapiens] >gb|ACE86532.1| insulin receptor substrate 1 protein, partial [synthetic construct] >emb|SJX44554.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAB27175.1| insulin receptor substrate-1 [Homo sapiens] >gb|AAH53895.1| Insulin receptor substrate 1 [Homo sapiens] >gb|AIC49075.1| IRS1, partial [synthetic construct]
1242 aa protein
accession:NP_005535.1
See full multiple alignment
Legend
Query sequence
nr matches
Landmark matches
Not aligned to query
Gap
Descriptions
Best hits
Show all columns of the table presenting best hits producing significant alignments
Select:AllNone
Selected:0
Alignments
Download
GenPept
Graphics
Distance tree of results
Multiple alignment
Show/hide columns of the table presenting best hits
Available columns
Select for downloading or viewing reports | Description | Max score | Total score | Query cover | E value | Ident | Accession |
---|---|---|---|---|---|---|---|
1 | 1906 | 1906 | 100% | 0.0 | 87.95% | NP_005535.1 | |
2 | 1039 | 1039 | 99% | 0.0 | 55.80% | XP_687702.4 | |
3 | 514 | 514 | 71% | 1e-159 | 42.13% | NP_001074681.1 | |
4 | 163 | 163 | 21% | 1e-39 | 34.58% | NP_001188772.1 | |
5 | 597 | 597 | 95% | 0.0 | 40.36% | XP_700746.4 |