Summary [?]
A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query:
NP_000448.3
hepatocyte nuclear factor 4-alpha isoform 2 [Homo sapiens] >ref|XP_047296091.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296092.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296093.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179377.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179378.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179379.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >sp|P41235.3| RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Homo sapiens] >dbj|BAG73239.1| hepatocyte nuclear factor 4, alpha, partial [synthetic construct] >gb|ABQ52204.1| hepatocyte nuclear factor 4, alpha [Homo sapiens] >gb|ADZ17380.1| hepatocyte nuclear factor 4 4 alpha variant 2 [Homo sapiens] >gb|EAW75925.1| hepatocyte nuclear factor 4, alpha, isoform CRA_e [Homo sapiens] >gb|KAI2594932.1| hepatocyte nuclear factor 4 alpha [Homo sapiens]
...
Query length:
474 aa
DOMAINS: and other(s) domains
...
hepatocyte nuclear factor 4, isoform F ctor 4, isoform F [Drosophila melanogaster]
...
hepatocyte nuclear factor 4, isoform F [Drosophila melanogaster] >gb|AHN54272.1| hepatocyte nuclear factor 4, isoform F [Drosophila melanogaster]
666 aa protein
accession:NP_001285758.1
hepatocyte nuclear factor 4-alpha isoform X3 tor 4-alpha isoform X1 [Danio aesculapii]
...
hepatocyte nuclear factor 4-alpha isoform X3 [Danio rerio] >ref|XP_056305167.1| hepatocyte nuclear factor 4-alpha isoform X1 [Danio aesculapii]
470 aa protein
accession:XP_021325423.1
hepatocyte nuclear factor 4-alpha isoform HNF4alpha2 pha isoform X1 [Mus caroli] >sp|P49698.2| RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Mus musculus] >gb|AAH39220.1| Hepatic nuclear factor 4, alpha [Mus musculus] >gb|AAX90602.1| hepatic nuclear factor 4 alpha [Mus musculus]
...
hepatocyte nuclear factor 4-alpha isoform HNF4alpha2 [Mus musculus] >ref|XP_021036484.1| hepatocyte nuclear factor 4-alpha isoform X1 [Mus caroli] >sp|P49698.2| RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Mus musculus] >gb|AAH39220.1| Hepatic nuclear factor 4, alpha [Mus musculus] >gb|AAX90602.1| hepatic nuclear factor 4 alpha [Mus musculus]
474 aa protein
accession:NP_032287.2
hepatocyte nuclear factor 4-alpha isoform X1 tor 4-alpha isoform X2 [Mus caroli]
...
hepatocyte nuclear factor 4-alpha isoform X1 [Mus musculus] >ref|XP_021036490.1| hepatocyte nuclear factor 4-alpha isoform X2 [Mus caroli]
464 aa protein
accession:XP_006498850.1
Query: hepatocyte nuclear factor 4-alpha isoform 2 ctor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296092.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296093.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179377.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179378.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179379.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >sp|P41235.3| RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Homo sapiens] >dbj|BAG73239.1| hepatocyte nuclear factor 4, alpha, partial [synthetic construct] >gb|ABQ52204.1| hepatocyte nuclear factor 4, alpha [Homo sapiens] >gb|ADZ17380.1| hepatocyte nuclear factor 4 4 alpha variant 2 [Homo sapiens] >gb|EAW75925.1| hepatocyte nuclear factor 4, alpha, isoform CRA_e [Homo sapiens] >gb|KAI2594932.1| hepatocyte nuclear factor 4 alpha [Homo sapiens]
...
hepatocyte nuclear factor 4-alpha isoform 2 [Homo sapiens] >ref|XP_047296091.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296092.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296093.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179377.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179378.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179379.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >sp|P41235.3| RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Homo sapiens] >dbj|BAG73239.1| hepatocyte nuclear factor 4, alpha, partial [synthetic construct] >gb|ABQ52204.1| hepatocyte nuclear factor 4, alpha [Homo sapiens] >gb|ADZ17380.1| hepatocyte nuclear factor 4 4 alpha variant 2 [Homo sapiens] >gb|EAW75925.1| hepatocyte nuclear factor 4, alpha, isoform CRA_e [Homo sapiens] >gb|KAI2594932.1| hepatocyte nuclear factor 4 alpha [Homo sapiens]
474 aa protein
accession:NP_000448.3
hepatocyte nuclear factor 4-alpha isoform 1 ctor 4-alpha isoform X2 [Homo sapiens] >ref|XP_054179380.1| hepatocyte nuclear factor 4-alpha isoform X2 [Homo sapiens] >gb|ADZ17371.1| hepatocyte nuclear factor 4 4 alpha variant 1 [Homo sapiens] >gb|KAI2594933.1| hepatocyte nuclear factor 4 alpha [Homo sapiens] >gb|KAI4005641.1| hepatocyte nuclear factor 4 alpha [Homo sapiens]
...
hepatocyte nuclear factor 4-alpha isoform 1 [Homo sapiens] >ref|XP_047296094.1| hepatocyte nuclear factor 4-alpha isoform X2 [Homo sapiens] >ref|XP_054179380.1| hepatocyte nuclear factor 4-alpha isoform X2 [Homo sapiens] >gb|ADZ17371.1| hepatocyte nuclear factor 4 4 alpha variant 1 [Homo sapiens] >gb|KAI2594933.1| hepatocyte nuclear factor 4 alpha [Homo sapiens] >gb|KAI4005641.1| hepatocyte nuclear factor 4 alpha [Homo sapiens]
464 aa protein
accession:NP_849180.1
DOMAINS: and other(s) domains
...
hepatocyte nuclear factor 4, isoform F [Drosophila melanogaster] >gb|AHN54272.1| hepatocyte nuclear factor 4, isoform F [Drosophila melanogaster]
666 aa protein
accession:NP_001285758.1
hepatocyte nuclear factor 4-alpha isoform X3 [Danio rerio] >ref|XP_056305167.1| hepatocyte nuclear factor 4-alpha isoform X1 [Danio aesculapii]
470 aa protein
accession:XP_021325423.1
hepatocyte nuclear factor 4-alpha isoform HNF4alpha2 [Mus musculus] >ref|XP_021036484.1| hepatocyte nuclear factor 4-alpha isoform X1 [Mus caroli] >sp|P49698.2| RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Mus musculus] >gb|AAH39220.1| Hepatic nuclear factor 4, alpha [Mus musculus] >gb|AAX90602.1| hepatic nuclear factor 4 alpha [Mus musculus]
474 aa protein
accession:NP_032287.2
hepatocyte nuclear factor 4-alpha isoform X1 [Mus musculus] >ref|XP_021036490.1| hepatocyte nuclear factor 4-alpha isoform X2 [Mus caroli]
464 aa protein
accession:XP_006498850.1
hepatocyte nuclear factor 4-alpha isoform 2 [Homo sapiens] >ref|XP_047296091.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296092.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_047296093.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179377.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179378.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >ref|XP_054179379.1| hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens] >sp|P41235.3| RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Homo sapiens] >dbj|BAG73239.1| hepatocyte nuclear factor 4, alpha, partial [synthetic construct] >gb|ABQ52204.1| hepatocyte nuclear factor 4, alpha [Homo sapiens] >gb|ADZ17380.1| hepatocyte nuclear factor 4 4 alpha variant 2 [Homo sapiens] >gb|EAW75925.1| hepatocyte nuclear factor 4, alpha, isoform CRA_e [Homo sapiens] >gb|KAI2594932.1| hepatocyte nuclear factor 4 alpha [Homo sapiens]
474 aa protein
accession:NP_000448.3
hepatocyte nuclear factor 4-alpha isoform 1 [Homo sapiens] >ref|XP_047296094.1| hepatocyte nuclear factor 4-alpha isoform X2 [Homo sapiens] >ref|XP_054179380.1| hepatocyte nuclear factor 4-alpha isoform X2 [Homo sapiens] >gb|ADZ17371.1| hepatocyte nuclear factor 4 4 alpha variant 1 [Homo sapiens] >gb|KAI2594933.1| hepatocyte nuclear factor 4 alpha [Homo sapiens] >gb|KAI4005641.1| hepatocyte nuclear factor 4 alpha [Homo sapiens]
464 aa protein
accession:NP_849180.1
See full multiple alignment
Legend
Query sequence
nr matches
Landmark matches
Not aligned to query
Gap
Descriptions
Best hits
Show all columns of the table presenting best hits producing significant alignments
Select:AllNone
Selected:0
Alignments
Download
GenPept
Graphics
Distance tree of results
Multiple alignment
Show/hide columns of the table presenting best hits
Available columns
| Select for downloading or viewing reports | Description | Max score | Total score | Query cover | E value | Ident | Accession |
|---|---|---|---|---|---|---|---|
| 1 | 954 | 954 | 100% | 0.0 | 97.68% | NP_849180.1 | |
| 2 | 948 | 948 | 100% | 0.0 | 95.78% | NP_032287.2 | |
| 3 | 787 | 787 | 100% | 0.0 | 79.96% | XP_021325423.1 | |
| 4 | 468 | 468 | 68% | 9e-159 | 67.26% | NP_001285758.1 | |
| 5 | 915 | 915 | 100% | 0.0 | 93.46% | XP_006498850.1 |