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A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query: NP_000184.1 sonic hedgehog protein isoform 1 preproprotein [Homo sapiens] >sp|Q15465.1| RecName: Full=Sonic hedgehog protein; Short=SHH; AltName: Full=HHG-1; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; Contains: RecName: Full=Sonic hedgehog protein N-product; Short=ShhN; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; Flags: Precursor [Homo sapiens] >pdb|7E2I|G Chain G, Sonic hedgehog protein [Homo sapiens] >gb|AAI11926.1| SHH protein, partial [synthetic construct] >gb|AAA62179.1| sonic hedgehog protein [Homo sapiens] >gb|AAQ87879.1| sonic hedgehog homolog (Drosophila) [Homo sapiens] >gb|AAS01990.1| unknown [Homo sapiens] >gb|EAL23913.1| sonic hedgehog homolog (Drosophila) [Homo sapiens] ... Query length: 462 aa
Warthog protein 4 N-product l=Warthog protein 4; AltName: Full=Protein M75; Contains: RecName: Full=Warthog protein 4 N-product; Contains: RecName: Full=Warthog protein 4 C-product; Flags: Precursor [Caenorhabditis elegans] >emb|CAB01902.2| Warthog protein 4 N-product [Caenorhabditis elegans] ...
Warthog protein 4 N-product [Caenorhabditis elegans] >sp|Q94129.2| RecName: Full=Warthog protein 4; AltName: Full=Protein M75; Contains: RecName: Full=Warthog protein 4 N-product; Contains: RecName: Full=Warthog protein 4 C-product; Flags: Precursor [Caenorhabditis elegans] >emb|CAB01902.2| Warthog protein 4 N-product [Caenorhabditis elegans]
557 aa protein
accession:NP_510593.1
sonic hedgehog protein precursor ic hedgehog protein; Short=SHHA; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; AltName: Full=VHH-1; Contains: RecName: Full=Sonic hedgehog protein A N-product; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; AltName: Full=Sonic hedgehog protein N-product; Short=ShhN; Flags: Precursor [Danio rerio] >gb|AAA20998.1| vhh-1 [Danio rerio] >gb|AAC59742.1| sonic hedgehog [Danio rerio] >gb|AAD47913.1| sonic hedgehog protein [Danio rerio] >gb|AAI62395.1| Shha protein [Danio rerio] >emb|CAA84738.1| sonic hedgehog [Danio rerio] ...
sonic hedgehog protein precursor [Danio rerio] >sp|Q92008.1| RecName: Full=Sonic hedgehog protein; Short=SHHA; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; AltName: Full=VHH-1; Contains: RecName: Full=Sonic hedgehog protein A N-product; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; AltName: Full=Sonic hedgehog protein N-product; Short=ShhN; Flags: Precursor [Danio rerio] >gb|AAA20998.1| vhh-1 [Danio rerio] >gb|AAC59742.1| sonic hedgehog [Danio rerio] >gb|AAD47913.1| sonic hedgehog protein [Danio rerio] >gb|AAI62395.1| Shha protein [Danio rerio] >emb|CAA84738.1| sonic hedgehog [Danio rerio]
418 aa protein
accession:NP_571138.1
hedgehog 936.4| RecName: Full=Protein hedgehog; Contains: RecName: Full=Protein hedgehog N-product; Short=Hh-Np; Short=N-Hh; Flags: Precursor [Drosophila melanogaster] >pdb|6TD6|B Chain B, Protein hedgehog [Drosophila melanogaster] >gb|AAB28646.1| segment polarity gene hedgehog [Drosophila sp. (in: flies)] >gb|AAA16458.1| hedgehog protein [Drosophila melanogaster] >gb|ABC66186.1| hedgehog [Drosophila melanogaster] ...
hedgehog [Drosophila melanogaster] >sp|Q02936.4| RecName: Full=Protein hedgehog; Contains: RecName: Full=Protein hedgehog N-product; Short=Hh-Np; Short=N-Hh; Flags: Precursor [Drosophila melanogaster] >pdb|6TD6|B Chain B, Protein hedgehog [Drosophila melanogaster] >gb|AAB28646.1| segment polarity gene hedgehog [Drosophila sp. (in: flies)] >gb|AAA16458.1| hedgehog protein [Drosophila melanogaster] >gb|ABC66186.1| hedgehog [Drosophila melanogaster]
471 aa protein
accession:NP_001034065.1
sonic hedgehog protein isoform 1 precursor g protein; Short=SHH; AltName: Full=HHG-1; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; Contains: RecName: Full=Sonic hedgehog protein N-product; Short=ShhN; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; AltName: Full=Sonic hedgehog protein 19 kDa product; Flags: Precursor [Mus musculus] >gb|AAB34105.1| Hhg-1 product [mice, Peptide, 437 aa] [Mus sp.] >gb|AAH63087.1| Sonic hedgehog [Mus musculus] >gb|EDL37231.1| sonic hedgehog [Mus musculus] >emb|CAA53922.1| sonic hedgehog [Mus musculus] >dbj|BAC36956.1| unnamed protein product [Mus musculus] ...
sonic hedgehog protein isoform 1 precursor [Mus musculus] >sp|Q62226.2| RecName: Full=Sonic hedgehog protein; Short=SHH; AltName: Full=HHG-1; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; Contains: RecName: Full=Sonic hedgehog protein N-product; Short=ShhN; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; AltName: Full=Sonic hedgehog protein 19 kDa product; Flags: Precursor [Mus musculus] >gb|AAB34105.1| Hhg-1 product [mice, Peptide, 437 aa] [Mus sp.] >gb|AAH63087.1| Sonic hedgehog [Mus musculus] >gb|EDL37231.1| sonic hedgehog [Mus musculus] >emb|CAA53922.1| sonic hedgehog [Mus musculus] >dbj|BAC36956.1| unnamed protein product [Mus musculus]
437 aa protein
accession:NP_033196.1
Query: sonic hedgehog protein isoform 1 preproprotein otein; Short=SHH; AltName: Full=HHG-1; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; Contains: RecName: Full=Sonic hedgehog protein N-product; Short=ShhN; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; Flags: Precursor [Homo sapiens] >pdb|7E2I|G Chain G, Sonic hedgehog protein [Homo sapiens] >gb|AAI11926.1| SHH protein, partial [synthetic construct] >gb|AAA62179.1| sonic hedgehog protein [Homo sapiens] >gb|AAQ87879.1| sonic hedgehog homolog (Drosophila) [Homo sapiens] >gb|AAS01990.1| unknown [Homo sapiens] >gb|EAL23913.1| sonic hedgehog homolog (Drosophila) [Homo sapiens] ...
sonic hedgehog protein isoform 1 preproprotein [Homo sapiens] >sp|Q15465.1| RecName: Full=Sonic hedgehog protein; Short=SHH; AltName: Full=HHG-1; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; Contains: RecName: Full=Sonic hedgehog protein N-product; Short=ShhN; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; Flags: Precursor [Homo sapiens] >pdb|7E2I|G Chain G, Sonic hedgehog protein [Homo sapiens] >gb|AAI11926.1| SHH protein, partial [synthetic construct] >gb|AAA62179.1| sonic hedgehog protein [Homo sapiens] >gb|AAQ87879.1| sonic hedgehog homolog (Drosophila) [Homo sapiens] >gb|AAS01990.1| unknown [Homo sapiens] >gb|EAL23913.1| sonic hedgehog homolog (Drosophila) [Homo sapiens]
462 aa protein
accession:NP_000184.1
sonic hedgehog protein isoform X1 hog protein isoform X1 [Homo sapiens] >ref|XP_054214781.1| sonic hedgehog protein isoform X1 [Homo sapiens] >ref|XP_054214782.1| sonic hedgehog protein isoform X1 [Homo sapiens] ...
sonic hedgehog protein isoform X1 [Homo sapiens] >ref|XP_011514782.1| sonic hedgehog protein isoform X1 [Homo sapiens] >ref|XP_054214781.1| sonic hedgehog protein isoform X1 [Homo sapiens] >ref|XP_054214782.1| sonic hedgehog protein isoform X1 [Homo sapiens]
375 aa protein
accession:XP_011514781.1

Descriptions

Best hits

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Best hits producing significant alignments
Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession
1
sonic hedgehog protein isoform 1 precursor [Mus musculus] >sp|Q62226.2| RecName: Full=Sonic hedgehog protein; Short=SHH; AltName: Full=HHG-1; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; Contains: RecName: Full=Sonic hedgehog protein N-product; Short=ShhN; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; AltName: Full=Sonic hedgehog protein 19 kDa product; Flags: Precursor [Mus musculus] >gb|AAB34105.1| Hhg-1 product [mice, Peptide, 437 aa] [Mus sp.] >gb|AAH63087.1| Sonic hedgehog [Mus musculus] >gb|EDL37231.1| sonic hedgehog [Mus musculus] >emb|CAA53922.1| sonic hedgehog [Mus musculus] >dbj|BAC36956.1| unnamed protein product [Mus musculus]
781 781 100% 0.087.45% NP_033196.1
2
sonic hedgehog protein isoform X1 [Homo sapiens] >ref|XP_011514782.1| sonic hedgehog protein isoform X1 [Homo sapiens] >ref|XP_054214781.1| sonic hedgehog protein isoform X1 [Homo sapiens] >ref|XP_054214782.1| sonic hedgehog protein isoform X1 [Homo sapiens]
734 734 78% 0.099.45% XP_011514781.1
3
sonic hedgehog protein precursor [Danio rerio] >sp|Q92008.1| RecName: Full=Sonic hedgehog protein; Short=SHHA; AltName: Full=Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Short=ShhNC; AltName: Full=VHH-1; Contains: RecName: Full=Sonic hedgehog protein A N-product; AltName: Full=Shh N-terminal processed signaling domains; Short=ShhNp; AltName: Full=Sonic hedgehog protein N-product; Short=ShhN; Flags: Precursor [Danio rerio] >gb|AAA20998.1| vhh-1 [Danio rerio] >gb|AAC59742.1| sonic hedgehog [Danio rerio] >gb|AAD47913.1| sonic hedgehog protein [Danio rerio] >gb|AAI62395.1| Shha protein [Danio rerio] >emb|CAA84738.1| sonic hedgehog [Danio rerio]
558 558 100% 0.064.50% NP_571138.1
4
hedgehog [Drosophila melanogaster] >sp|Q02936.4| RecName: Full=Protein hedgehog; Contains: RecName: Full=Protein hedgehog N-product; Short=Hh-Np; Short=N-Hh; Flags: Precursor [Drosophila melanogaster] >pdb|6TD6|B Chain B, Protein hedgehog [Drosophila melanogaster] >gb|AAB28646.1| segment polarity gene hedgehog [Drosophila sp. (in: flies)] >gb|AAA16458.1| hedgehog protein [Drosophila melanogaster] >gb|ABC66186.1| hedgehog [Drosophila melanogaster]
332 332 96% 2e-10844.30% NP_001034065.1
5
Warthog protein 4 N-product [Caenorhabditis elegans] >sp|Q94129.2| RecName: Full=Warthog protein 4; AltName: Full=Protein M75; Contains: RecName: Full=Warthog protein 4 N-product; Contains: RecName: Full=Warthog protein 4 C-product; Flags: Precursor [Caenorhabditis elegans] >emb|CAB01902.2| Warthog protein 4 N-product [Caenorhabditis elegans]
63.9 63.9 39% 1e-0927.87% NP_510593.1