Summary [?]
A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query:
NP_004170.1
tryptophan 5-hydroxylase 1 [Homo sapiens] >sp|P17752.4| RecName: Full=Tryptophan 5-hydroxylase 1; AltName: Full=Tryptophan 5-monooxygenase 1 [Homo sapiens] >pdb|5L01|A Chain A, Tryptophan 5-hydroxylase 1 [Homo sapiens] >gb|AIC49892.1| TPH1, partial [synthetic construct] >emb|SJX39462.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI06740.1| Tryptophan hydroxylase 1 [Homo sapiens] >gb|EAW68421.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens] >gb|EAW68422.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens]
...
Query length:
444 aa
DOMAINS: and other(s) domains
...
tyrosine 3-monooxygenase isoform b onooxygenase isoform X2 [Pan paniscus] >gb|AAI43612.1| Tyrosine hydroxylase [Homo sapiens] >gb|EAX02493.1| tyrosine hydroxylase, isoform CRA_d [Homo sapiens] >gb|KAI2558113.1| tyrosine hydroxylase [Homo sapiens]
...
tyrosine 3-monooxygenase isoform b [Homo sapiens] >ref|XP_003816109.1| tyrosine 3-monooxygenase isoform X2 [Pan paniscus] >gb|AAI43612.1| Tyrosine hydroxylase [Homo sapiens] >gb|EAX02493.1| tyrosine hydroxylase, isoform CRA_d [Homo sapiens] >gb|KAI2558113.1| tyrosine hydroxylase [Homo sapiens]
497 aa protein
accession:NP_000351.2
phenylalanine 4-monooxygenase Phenylalanine-4-hydroxylase; Short=PAH; AltName: Full=Phe-4-monooxygenase; AltName: Full=Tryptophan 5-hydroxylase; Short=TRH; AltName: Full=Tryptophan 5-monooxygenase [Dictyostelium discoideum] >gb|EAL67992.1| phenylalanine 4-monooxygenase [Dictyostelium discoideum AX4]
...
phenylalanine 4-monooxygenase [Dictyostelium discoideum AX4] >sp|Q54XS1.1| RecName: Full=Phenylalanine-4-hydroxylase; Short=PAH; AltName: Full=Phe-4-monooxygenase; AltName: Full=Tryptophan 5-hydroxylase; Short=TRH; AltName: Full=Tryptophan 5-monooxygenase [Dictyostelium discoideum] >gb|EAL67992.1| phenylalanine 4-monooxygenase [Dictyostelium discoideum AX4]
441 aa protein
accession:XP_641959.1
tryptophan hydroxylase neuronal l [synthetic construct] >gb|AAF47444.1| tryptophan hydroxylase neuronal [Drosophila melanogaster] >gb|AAN71173.1| GH12537p [Drosophila melanogaster] >gb|ACL90131.1| Trh-PA [synthetic construct] >gb|AOQ13189.1| Trh-PA [synthetic construct]
...
tryptophan hydroxylase neuronal [Drosophila melanogaster] >gb|ACL85257.1| Trh-PA, partial [synthetic construct] >gb|AAF47444.1| tryptophan hydroxylase neuronal [Drosophila melanogaster] >gb|AAN71173.1| GH12537p [Drosophila melanogaster] >gb|ACL90131.1| Trh-PA [synthetic construct] >gb|AOQ13189.1| Trh-PA [synthetic construct]
555 aa protein
accession:NP_612080.1
tryptophan 5-hydroxylase 1a ein [Danio rerio]
...
tryptophan 5-hydroxylase 1a [Danio rerio] >gb|AAH59550.1| Tph1a protein [Danio rerio]
483 aa protein
accession:NP_840091.2
Query: tryptophan 5-hydroxylase 1 ll=Tryptophan 5-hydroxylase 1; AltName: Full=Tryptophan 5-monooxygenase 1 [Homo sapiens] >pdb|5L01|A Chain A, Tryptophan 5-hydroxylase 1 [Homo sapiens] >gb|AIC49892.1| TPH1, partial [synthetic construct] >emb|SJX39462.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI06740.1| Tryptophan hydroxylase 1 [Homo sapiens] >gb|EAW68421.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens] >gb|EAW68422.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens]
...
tryptophan 5-hydroxylase 1 [Homo sapiens] >sp|P17752.4| RecName: Full=Tryptophan 5-hydroxylase 1; AltName: Full=Tryptophan 5-monooxygenase 1 [Homo sapiens] >pdb|5L01|A Chain A, Tryptophan 5-hydroxylase 1 [Homo sapiens] >gb|AIC49892.1| TPH1, partial [synthetic construct] >emb|SJX39462.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI06740.1| Tryptophan hydroxylase 1 [Homo sapiens] >gb|EAW68421.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens] >gb|EAW68422.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens]
444 aa protein
accession:NP_004170.1
tryptophan 5-hydroxylase 1 isoform 1 oxylase 1 isoform 1 [Mus musculus] >ref|XP_036008805.1| tryptophan 5-hydroxylase 1 isoform X1 [Mus musculus] >sp|P17532.1| RecName: Full=Tryptophan 5-hydroxylase 1; AltName: Full=Tryptophan 5-monooxygenase 1 [Mus musculus] >gb|AAA63401.1| tryptophan hydroxylase [Mus musculus] >gb|AAH72582.1| Tryptophan hydroxylase 1 [Mus musculus] >gb|EDL22930.1| tryptophan hydroxylase 1 [Mus musculus] >dbj|BAE26925.1| unnamed protein product [Mus musculus] >dbj|BAE26950.1| unnamed protein product [Mus musculus]
...
tryptophan 5-hydroxylase 1 isoform 1 [Mus musculus] >ref|NP_033440.1| tryptophan 5-hydroxylase 1 isoform 1 [Mus musculus] >ref|XP_036008805.1| tryptophan 5-hydroxylase 1 isoform X1 [Mus musculus] >sp|P17532.1| RecName: Full=Tryptophan 5-hydroxylase 1; AltName: Full=Tryptophan 5-monooxygenase 1 [Mus musculus] >gb|AAA63401.1| tryptophan hydroxylase [Mus musculus] >gb|AAH72582.1| Tryptophan hydroxylase 1 [Mus musculus] >gb|EDL22930.1| tryptophan hydroxylase 1 [Mus musculus] >dbj|BAE26925.1| unnamed protein product [Mus musculus] >dbj|BAE26950.1| unnamed protein product [Mus musculus]
447 aa protein
accession:NP_001129556.1
DOMAINS: and other(s) domains
...
tyrosine 3-monooxygenase isoform b [Homo sapiens] >ref|XP_003816109.1| tyrosine 3-monooxygenase isoform X2 [Pan paniscus] >gb|AAI43612.1| Tyrosine hydroxylase [Homo sapiens] >gb|EAX02493.1| tyrosine hydroxylase, isoform CRA_d [Homo sapiens] >gb|KAI2558113.1| tyrosine hydroxylase [Homo sapiens]
497 aa protein
accession:NP_000351.2
phenylalanine 4-monooxygenase [Dictyostelium discoideum AX4] >sp|Q54XS1.1| RecName: Full=Phenylalanine-4-hydroxylase; Short=PAH; AltName: Full=Phe-4-monooxygenase; AltName: Full=Tryptophan 5-hydroxylase; Short=TRH; AltName: Full=Tryptophan 5-monooxygenase [Dictyostelium discoideum] >gb|EAL67992.1| phenylalanine 4-monooxygenase [Dictyostelium discoideum AX4]
441 aa protein
accession:XP_641959.1
tryptophan hydroxylase neuronal [Drosophila melanogaster] >gb|ACL85257.1| Trh-PA, partial [synthetic construct] >gb|AAF47444.1| tryptophan hydroxylase neuronal [Drosophila melanogaster] >gb|AAN71173.1| GH12537p [Drosophila melanogaster] >gb|ACL90131.1| Trh-PA [synthetic construct] >gb|AOQ13189.1| Trh-PA [synthetic construct]
555 aa protein
accession:NP_612080.1
tryptophan 5-hydroxylase 1a [Danio rerio] >gb|AAH59550.1| Tph1a protein [Danio rerio]
483 aa protein
accession:NP_840091.2
tryptophan 5-hydroxylase 1 [Homo sapiens] >sp|P17752.4| RecName: Full=Tryptophan 5-hydroxylase 1; AltName: Full=Tryptophan 5-monooxygenase 1 [Homo sapiens] >pdb|5L01|A Chain A, Tryptophan 5-hydroxylase 1 [Homo sapiens] >gb|AIC49892.1| TPH1, partial [synthetic construct] >emb|SJX39462.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI06740.1| Tryptophan hydroxylase 1 [Homo sapiens] >gb|EAW68421.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens] >gb|EAW68422.1| tryptophan hydroxylase 1 (tryptophan 5-monooxygenase), isoform CRA_b [Homo sapiens]
444 aa protein
accession:NP_004170.1
tryptophan 5-hydroxylase 1 isoform 1 [Mus musculus] >ref|NP_033440.1| tryptophan 5-hydroxylase 1 isoform 1 [Mus musculus] >ref|XP_036008805.1| tryptophan 5-hydroxylase 1 isoform X1 [Mus musculus] >sp|P17532.1| RecName: Full=Tryptophan 5-hydroxylase 1; AltName: Full=Tryptophan 5-monooxygenase 1 [Mus musculus] >gb|AAA63401.1| tryptophan hydroxylase [Mus musculus] >gb|AAH72582.1| Tryptophan hydroxylase 1 [Mus musculus] >gb|EDL22930.1| tryptophan hydroxylase 1 [Mus musculus] >dbj|BAE26925.1| unnamed protein product [Mus musculus] >dbj|BAE26950.1| unnamed protein product [Mus musculus]
447 aa protein
accession:NP_001129556.1
See full multiple alignment
Legend
Query sequence
nr matches
Landmark matches
Not aligned to query
Gap
Descriptions
Best hits
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Alignments
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Graphics
Distance tree of results
Multiple alignment
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Available columns
Select for downloading or viewing reports | Description | Max score | Total score | Query cover | E value | Ident | Accession |
---|---|---|---|---|---|---|---|
1 | 844 | 844 | 100% | 0.0 | 89.49% | NP_001129556.1 | |
2 | 761 | 761 | 99% | 0.0 | 78.33% | NP_840091.2 | |
3 | 550 | 550 | 95% | 0.0 | 58.45% | NP_612080.1 | |
4 | 462 | 462 | 94% | 3e-160 | 51.53% | XP_641959.1 | |
5 | 447 | 447 | 94% | 3e-153 | 50.12% | NP_000351.2 |