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Summary [?]

A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query: NP_014668.1 NAD-dependent histone deacetylase HST3 [Saccharomyces cerevisiae S288C] >sp|P53687.1| RecName: Full=NAD-dependent histone deacetylase HST3; AltName: Full=Homologous to SIR2 protein 3; AltName: Full=Regulatory protein SIR2 homolog 3 [Saccharomyces cerevisiae S288C] >gb|AAA81034.1| Hst3p [Saccharomyces cerevisiae] >gb|AJT76356.1| Hst3p [Saccharomyces cerevisiae YJM451] >gb|AJT77344.1| Hst3p [Saccharomyces cerevisiae YJM456] >gb|AJT81764.1| Hst3p [Saccharomyces cerevisiae YJM689] >gb|AJT87152.1| Hst3p [Saccharomyces cerevisiae YJM1083] >gb|AJT89121.1| Hst3p [Saccharomyces cerevisiae YJM1199] >gb|AJT89611.1| Hst3p [Saccharomyces cerevisiae YJM1202] >gb|AJT92954.1| Hst3p [Saccharomyces cerevisiae YJM1273] >gb|AJT93923.1| Hst3p [Saccharomyces cerevisiae YJM1307] >gb|AJT94407.1| Hst3p [Saccharomyces cerevisiae YJM1311] >gb|AJT97350.1| Hst3p [Saccharomyces cerevisiae YJM1342] >gb|AJT98828.1| Hst3p [Saccharomyces cerevisiae YJM1381] >gb|AJT99321.1| Hst3p [Saccharomyces cerevisiae YJM1383] >gb|AJU01274.1| Hst3p [Saccharomyces cerevisiae YJM1388] >gb|AJU01757.1| Hst3p [Saccharomyces cerevisiae YJM1389] >gb|AJU02734.1| Hst3p [Saccharomyces cerevisiae YJM1400] >gb|AJU03226.1| Hst3p [Saccharomyces cerevisiae YJM1401] >gb|AJU03726.1| Hst3p [Saccharomyces cerevisiae YJM1402] >gb|AJU06661.1| Hst3p [Saccharomyces cerevisiae YJM1434] >gb|AJU07642.1| Hst3p [Saccharomyces cerevisiae YJM1443] >gb|AJU09082.1| Hst3p [Saccharomyces cerevisiae YJM1450] >gb|AJU09571.1| Hst3p [Saccharomyces cerevisiae YJM1460] >gb|AJU11529.1| Hst3p [Saccharomyces cerevisiae YJM1479] >gb|AJU13491.1| Hst3p [Saccharomyces cerevisiae YJM1573] >gb|AJU14474.1| Hst3p [Saccharomyces cerevisiae YJM1592] ... Query length: 447 aa
NAD-dependent protein deacetylase sirtuin-1 isoform a acetylase sirtuin-1; Short=hSIRT1; AltName: Full=NAD-dependent protein deacylase sirtuin-1; AltName: Full=Regulatory protein SIR2 homolog 1; AltName: Full=SIR2-like protein 1; Short=hSIR2; Contains: RecName: Full=SirtT1 75 kDa fragment; Short=75SirT1 [Homo sapiens] >gb|AAD40849.2| sirtuin type 1 [Homo sapiens] >gb|AAG38486.1| SIR2alpha protein [Homo sapiens] >gb|ABB72675.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) [Homo sapiens] >gb|EAW54258.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), isoform CRA_a [Homo sapiens] >gb|EAW54259.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), isoform CRA_a [Homo sapiens] ...
NAD-dependent protein deacetylase sirtuin-1 isoform a [Homo sapiens] >sp|Q96EB6.2| RecName: Full=NAD-dependent protein deacetylase sirtuin-1; Short=hSIRT1; AltName: Full=NAD-dependent protein deacylase sirtuin-1; AltName: Full=Regulatory protein SIR2 homolog 1; AltName: Full=SIR2-like protein 1; Short=hSIR2; Contains: RecName: Full=SirtT1 75 kDa fragment; Short=75SirT1 [Homo sapiens] >gb|AAD40849.2| sirtuin type 1 [Homo sapiens] >gb|AAG38486.1| SIR2alpha protein [Homo sapiens] >gb|ABB72675.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) [Homo sapiens] >gb|EAW54258.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), isoform CRA_a [Homo sapiens] >gb|EAW54259.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), isoform CRA_a [Homo sapiens]
747 aa protein
accession:NP_036370.2
NAD-dependent protein deacetylase sirtuin-1 isoform 2 us] ...
NAD-dependent protein deacetylase sirtuin-1 isoform 2 [Mus musculus] >dbj|BAE25766.1| unnamed protein product [Mus musculus]
698 aa protein
accession:NP_001153061.1
NAD-dependent protein deacetylase sirtuin-1 isoform X2 ...
NAD-dependent protein deacetylase sirtuin-1 isoform X2 [Danio rerio]
695 aa protein
accession:XP_005173091.1
Query: NAD-dependent histone deacetylase HST3 dent histone deacetylase HST3; AltName: Full=Homologous to SIR2 protein 3; AltName: Full=Regulatory protein SIR2 homolog 3 [Saccharomyces cerevisiae S288C] >gb|AAA81034.1| Hst3p [Saccharomyces cerevisiae] >gb|AJT76356.1| Hst3p [Saccharomyces cerevisiae YJM451] >gb|AJT77344.1| Hst3p [Saccharomyces cerevisiae YJM456] >gb|AJT81764.1| Hst3p [Saccharomyces cerevisiae YJM689] >gb|AJT87152.1| Hst3p [Saccharomyces cerevisiae YJM1083] >gb|AJT89121.1| Hst3p [Saccharomyces cerevisiae YJM1199] >gb|AJT89611.1| Hst3p [Saccharomyces cerevisiae YJM1202] >gb|AJT92954.1| Hst3p [Saccharomyces cerevisiae YJM1273] >gb|AJT93923.1| Hst3p [Saccharomyces cerevisiae YJM1307] >gb|AJT94407.1| Hst3p [Saccharomyces cerevisiae YJM1311] >gb|AJT97350.1| Hst3p [Saccharomyces cerevisiae YJM1342] >gb|AJT98828.1| Hst3p [Saccharomyces cerevisiae YJM1381] >gb|AJT99321.1| Hst3p [Saccharomyces cerevisiae YJM1383] >gb|AJU01274.1| Hst3p [Saccharomyces cerevisiae YJM1388] >gb|AJU01757.1| Hst3p [Saccharomyces cerevisiae YJM1389] >gb|AJU02734.1| Hst3p [Saccharomyces cerevisiae YJM1400] >gb|AJU03226.1| Hst3p [Saccharomyces cerevisiae YJM1401] >gb|AJU03726.1| Hst3p [Saccharomyces cerevisiae YJM1402] >gb|AJU06661.1| Hst3p [Saccharomyces cerevisiae YJM1434] >gb|AJU07642.1| Hst3p [Saccharomyces cerevisiae YJM1443] >gb|AJU09082.1| Hst3p [Saccharomyces cerevisiae YJM1450] >gb|AJU09571.1| Hst3p [Saccharomyces cerevisiae YJM1460] >gb|AJU11529.1| Hst3p [Saccharomyces cerevisiae YJM1479] >gb|AJU13491.1| Hst3p [Saccharomyces cerevisiae YJM1573] >gb|AJU14474.1| Hst3p [Saccharomyces cerevisiae YJM1592] ...
NAD-dependent histone deacetylase HST3 [Saccharomyces cerevisiae S288C] >sp|P53687.1| RecName: Full=NAD-dependent histone deacetylase HST3; AltName: Full=Homologous to SIR2 protein 3; AltName: Full=Regulatory protein SIR2 homolog 3 [Saccharomyces cerevisiae S288C] >gb|AAA81034.1| Hst3p [Saccharomyces cerevisiae] >gb|AJT76356.1| Hst3p [Saccharomyces cerevisiae YJM451] >gb|AJT77344.1| Hst3p [Saccharomyces cerevisiae YJM456] >gb|AJT81764.1| Hst3p [Saccharomyces cerevisiae YJM689] >gb|AJT87152.1| Hst3p [Saccharomyces cerevisiae YJM1083] >gb|AJT89121.1| Hst3p [Saccharomyces cerevisiae YJM1199] >gb|AJT89611.1| Hst3p [Saccharomyces cerevisiae YJM1202] >gb|AJT92954.1| Hst3p [Saccharomyces cerevisiae YJM1273] >gb|AJT93923.1| Hst3p [Saccharomyces cerevisiae YJM1307] >gb|AJT94407.1| Hst3p [Saccharomyces cerevisiae YJM1311] >gb|AJT97350.1| Hst3p [Saccharomyces cerevisiae YJM1342] >gb|AJT98828.1| Hst3p [Saccharomyces cerevisiae YJM1381] >gb|AJT99321.1| Hst3p [Saccharomyces cerevisiae YJM1383] >gb|AJU01274.1| Hst3p [Saccharomyces cerevisiae YJM1388] >gb|AJU01757.1| Hst3p [Saccharomyces cerevisiae YJM1389] >gb|AJU02734.1| Hst3p [Saccharomyces cerevisiae YJM1400] >gb|AJU03226.1| Hst3p [Saccharomyces cerevisiae YJM1401] >gb|AJU03726.1| Hst3p [Saccharomyces cerevisiae YJM1402] >gb|AJU06661.1| Hst3p [Saccharomyces cerevisiae YJM1434] >gb|AJU07642.1| Hst3p [Saccharomyces cerevisiae YJM1443] >gb|AJU09082.1| Hst3p [Saccharomyces cerevisiae YJM1450] >gb|AJU09571.1| Hst3p [Saccharomyces cerevisiae YJM1460] >gb|AJU11529.1| Hst3p [Saccharomyces cerevisiae YJM1479] >gb|AJU13491.1| Hst3p [Saccharomyces cerevisiae YJM1573] >gb|AJU14474.1| Hst3p [Saccharomyces cerevisiae YJM1592]
447 aa protein
accession:NP_014668.1
Sir2 family histone deacetylase Hst4 endent protein deacetylase hst4; AltName: Full=Homologous to SIR2 protein 4; AltName: Full=Regulatory protein SIR2 homolog 4 [Schizosaccharomyces pombe 972h-] >gb|AAD53752.1| Hst4p [Schizosaccharomyces pombe] >emb|CAB66167.1| histone deacetylase, Sirtuin family, NAD-dependent Hst4 [Schizosaccharomyces pombe] ...
Sir2 family histone deacetylase Hst4 [Schizosaccharomyces pombe] >sp|Q9UR39.1| RecName: Full=NAD-dependent protein deacetylase hst4; AltName: Full=Homologous to SIR2 protein 4; AltName: Full=Regulatory protein SIR2 homolog 4 [Schizosaccharomyces pombe 972h-] >gb|AAD53752.1| Hst4p [Schizosaccharomyces pombe] >emb|CAB66167.1| histone deacetylase, Sirtuin family, NAD-dependent Hst4 [Schizosaccharomyces pombe]
415 aa protein
accession:NP_593659.1
NAD-dependent histone deacetylase HST4 dent histone deacetylase HST4; AltName: Full=Homologous to SIR2 protein 4; AltName: Full=Regulatory protein SIR2 homolog 4 [Saccharomyces cerevisiae S288C] >gb|AAS56025.1| YDR191W [Saccharomyces cerevisiae] >gb|AJU64280.1| Hst4p [Saccharomyces cerevisiae YJM428] >gb|EIW11398.1| Hst4p [Saccharomyces cerevisiae CEN.PK113-7D] >gb|WNF20010.1| HST4 [Saccharomyces cerevisiae synthetic construct] >gb|KAF1906493.1| NAD-dependent histone deacetylase HST4, partial [Saccharomyces cerevisiae] ...
NAD-dependent histone deacetylase HST4 [Saccharomyces cerevisiae S288C] >sp|P53688.1| RecName: Full=NAD-dependent histone deacetylase HST4; AltName: Full=Homologous to SIR2 protein 4; AltName: Full=Regulatory protein SIR2 homolog 4 [Saccharomyces cerevisiae S288C] >gb|AAS56025.1| YDR191W [Saccharomyces cerevisiae] >gb|AJU64280.1| Hst4p [Saccharomyces cerevisiae YJM428] >gb|EIW11398.1| Hst4p [Saccharomyces cerevisiae CEN.PK113-7D] >gb|WNF20010.1| HST4 [Saccharomyces cerevisiae synthetic construct] >gb|KAF1906493.1| NAD-dependent histone deacetylase HST4, partial [Saccharomyces cerevisiae]
370 aa protein
accession:NP_010477.3

Descriptions

Best hits

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Best hits producing significant alignments
Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession
1
Sir2 family histone deacetylase Hst4 [Schizosaccharomyces pombe] >sp|Q9UR39.1| RecName: Full=NAD-dependent protein deacetylase hst4; AltName: Full=Homologous to SIR2 protein 4; AltName: Full=Regulatory protein SIR2 homolog 4 [Schizosaccharomyces pombe 972h-] >gb|AAD53752.1| Hst4p [Schizosaccharomyces pombe] >emb|CAB66167.1| histone deacetylase, Sirtuin family, NAD-dependent Hst4 [Schizosaccharomyces pombe]
175 175 67% 6e-4938.16% NP_593659.1
2
NAD-dependent histone deacetylase HST4 [Saccharomyces cerevisiae S288C] >sp|P53688.1| RecName: Full=NAD-dependent histone deacetylase HST4; AltName: Full=Homologous to SIR2 protein 4; AltName: Full=Regulatory protein SIR2 homolog 4 [Saccharomyces cerevisiae S288C] >gb|AAS56025.1| YDR191W [Saccharomyces cerevisiae] >gb|AJU64280.1| Hst4p [Saccharomyces cerevisiae YJM428] >gb|EIW11398.1| Hst4p [Saccharomyces cerevisiae CEN.PK113-7D] >gb|WNF20010.1| HST4 [Saccharomyces cerevisiae synthetic construct] >gb|KAF1906493.1| NAD-dependent histone deacetylase HST4, partial [Saccharomyces cerevisiae]
159 159 66% 2e-4333.66% NP_010477.3
3
NAD-dependent protein deacetylase sirtuin-1 isoform a [Homo sapiens] >sp|Q96EB6.2| RecName: Full=NAD-dependent protein deacetylase sirtuin-1; Short=hSIRT1; AltName: Full=NAD-dependent protein deacylase sirtuin-1; AltName: Full=Regulatory protein SIR2 homolog 1; AltName: Full=SIR2-like protein 1; Short=hSIR2; Contains: RecName: Full=SirtT1 75 kDa fragment; Short=75SirT1 [Homo sapiens] >gb|AAD40849.2| sirtuin type 1 [Homo sapiens] >gb|AAG38486.1| SIR2alpha protein [Homo sapiens] >gb|ABB72675.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) [Homo sapiens] >gb|EAW54258.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), isoform CRA_a [Homo sapiens] >gb|EAW54259.1| sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), isoform CRA_a [Homo sapiens]
125 125 67% 2e-2931.39% NP_036370.2
4
NAD-dependent protein deacetylase sirtuin-1 isoform 2 [Mus musculus] >dbj|BAE25766.1| unnamed protein product [Mus musculus]
124 124 67% 3e-2931.39% NP_001153061.1
5
NAD-dependent protein deacetylase sirtuin-1 isoform X2 [Danio rerio]
123 123 67% 6e-2930.00% XP_005173091.1