Summary [?]
A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query:
NP_036807.1
tumor necrosis factor [Rattus norvegicus] >sp|P16599.1| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Rattus norvegicus] >gb|AAA16275.1| tumor necrosis factor [Rattus norvegicus] >gb|AAI07672.1| Tumor necrosis factor (TNF superfamily, member 2) [Rattus norvegicus] >gb|AAK53568.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53569.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53570.1| tumor necrosis factor alpha [Rattus norvegicus]
...
Query length:
235 aa
DOMAINS: and other(s) domains
...
tumor necrosis factor a (TNF superfamily, member 2) family, member 2) [Danio rerio] >gb|AAI65066.1| Tnfa protein [Danio rerio]
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tumor necrosis factor a (TNF superfamily, member 2) [Danio rerio] >gb|AAI24142.1| Tumor necrosis factor a (TNF superfamily, member 2) [Danio rerio] >gb|AAI65066.1| Tnfa protein [Danio rerio]
234 aa protein
accession:NP_998024.2
lymphotoxin-alpha precursor otoxin-alpha isoform X1 [Mus musculus] >sp|P09225.1| RecName: Full=Lymphotoxin-alpha; Short=LT-alpha; AltName: Full=TNF-beta; AltName: Full=Tumor necrosis factor ligand superfamily member 1; Flags: Precursor [Mus musculus] >gb|AAA18593.1| lymphotoxin-alpha [Mus musculus] >gb|AAA40460.1| lymphotoxin precursor [Mus musculus] >gb|AAC82485.1| LTA [Mus musculus] >gb|AAH99464.1| Lta protein [Mus musculus] >emb|CAA68330.1| lymphotoxin [Mus musculus]
...
lymphotoxin-alpha precursor [Mus musculus] >ref|XP_006523794.1| lymphotoxin-alpha isoform X1 [Mus musculus] >sp|P09225.1| RecName: Full=Lymphotoxin-alpha; Short=LT-alpha; AltName: Full=TNF-beta; AltName: Full=Tumor necrosis factor ligand superfamily member 1; Flags: Precursor [Mus musculus] >gb|AAA18593.1| lymphotoxin-alpha [Mus musculus] >gb|AAA40460.1| lymphotoxin precursor [Mus musculus] >gb|AAC82485.1| LTA [Mus musculus] >gb|AAH99464.1| Lta protein [Mus musculus] >emb|CAA68330.1| lymphotoxin [Mus musculus]
202 aa protein
accession:NP_034865.1
tumor necrosis factor tumor necrosis factor [Pan paniscus] >ref|XP_016810226.1| tumor necrosis factor isoform X1 [Pan troglodytes] >ref|XP_055245961.1| tumor necrosis factor [Gorilla gorilla gorilla] >sp|P01375.1| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Homo sapiens] >gb|AAX41550.1| tumor necrosis factor [synthetic construct] >emb|SJX40660.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAA36758.1| tumor necrosis factor precursor [Homo sapiens] >gb|AAA61200.1| tumor necrosis factor [Homo sapiens] >gb|AAD18091.1| tumor necrosis factor [Homo sapiens]
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tumor necrosis factor [Homo sapiens] >ref|XP_003831637.1| tumor necrosis factor [Pan paniscus] >ref|XP_016810226.1| tumor necrosis factor isoform X1 [Pan troglodytes] >ref|XP_055245961.1| tumor necrosis factor [Gorilla gorilla gorilla] >sp|P01375.1| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Homo sapiens] >gb|AAX41550.1| tumor necrosis factor [synthetic construct] >emb|SJX40660.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAA36758.1| tumor necrosis factor precursor [Homo sapiens] >gb|AAA61200.1| tumor necrosis factor [Homo sapiens] >gb|AAD18091.1| tumor necrosis factor [Homo sapiens]
233 aa protein
accession:NP_000585.2
Query: tumor necrosis factor e: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Rattus norvegicus] >gb|AAA16275.1| tumor necrosis factor [Rattus norvegicus] >gb|AAI07672.1| Tumor necrosis factor (TNF superfamily, member 2) [Rattus norvegicus] >gb|AAK53568.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53569.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53570.1| tumor necrosis factor alpha [Rattus norvegicus]
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tumor necrosis factor [Rattus norvegicus] >sp|P16599.1| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Rattus norvegicus] >gb|AAA16275.1| tumor necrosis factor [Rattus norvegicus] >gb|AAI07672.1| Tumor necrosis factor (TNF superfamily, member 2) [Rattus norvegicus] >gb|AAK53568.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53569.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53570.1| tumor necrosis factor alpha [Rattus norvegicus]
235 aa protein
accession:NP_036807.1
tumor necrosis factor isoform 1 mor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Mus musculus] >gb|AAA18594.1| tumor necrosis factor [Mus musculus] >gb|AAA40458.1| tumor necrosis factor precursor [Mus musculus] >gb|AAA40459.1| tumor necrosis factor [Mus musculus] >gb|AAC82484.1| TNF [Mus musculus] >gb|AAI17058.1| Tumor necrosis factor [Mus musculus]
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tumor necrosis factor isoform 1 [Mus musculus] >sp|P06804.2| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Mus musculus] >gb|AAA18594.1| tumor necrosis factor [Mus musculus] >gb|AAA40458.1| tumor necrosis factor precursor [Mus musculus] >gb|AAA40459.1| tumor necrosis factor [Mus musculus] >gb|AAC82484.1| TNF [Mus musculus] >gb|AAI17058.1| Tumor necrosis factor [Mus musculus]
235 aa protein
accession:NP_038721.1
tumor necrosis factor isoform 2 factor [Mus musculus] >gb|EDL26631.1| tumor necrosis factor, isoform CRA_a [Mus musculus]
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tumor necrosis factor isoform 2 [Mus musculus] >gb|AAA40462.1| tumor necrosis factor [Mus musculus] >gb|EDL26631.1| tumor necrosis factor, isoform CRA_a [Mus musculus]
219 aa protein
accession:NP_001265530.1
DOMAINS: and other(s) domains
...
tumor necrosis factor a (TNF superfamily, member 2) [Danio rerio] >gb|AAI24142.1| Tumor necrosis factor a (TNF superfamily, member 2) [Danio rerio] >gb|AAI65066.1| Tnfa protein [Danio rerio]
234 aa protein
accession:NP_998024.2
lymphotoxin-alpha precursor [Mus musculus] >ref|XP_006523794.1| lymphotoxin-alpha isoform X1 [Mus musculus] >sp|P09225.1| RecName: Full=Lymphotoxin-alpha; Short=LT-alpha; AltName: Full=TNF-beta; AltName: Full=Tumor necrosis factor ligand superfamily member 1; Flags: Precursor [Mus musculus] >gb|AAA18593.1| lymphotoxin-alpha [Mus musculus] >gb|AAA40460.1| lymphotoxin precursor [Mus musculus] >gb|AAC82485.1| LTA [Mus musculus] >gb|AAH99464.1| Lta protein [Mus musculus] >emb|CAA68330.1| lymphotoxin [Mus musculus]
202 aa protein
accession:NP_034865.1
tumor necrosis factor [Homo sapiens] >ref|XP_003831637.1| tumor necrosis factor [Pan paniscus] >ref|XP_016810226.1| tumor necrosis factor isoform X1 [Pan troglodytes] >ref|XP_055245961.1| tumor necrosis factor [Gorilla gorilla gorilla] >sp|P01375.1| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Homo sapiens] >gb|AAX41550.1| tumor necrosis factor [synthetic construct] >emb|SJX40660.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAA36758.1| tumor necrosis factor precursor [Homo sapiens] >gb|AAA61200.1| tumor necrosis factor [Homo sapiens] >gb|AAD18091.1| tumor necrosis factor [Homo sapiens]
233 aa protein
accession:NP_000585.2
tumor necrosis factor [Rattus norvegicus] >sp|P16599.1| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Rattus norvegicus] >gb|AAA16275.1| tumor necrosis factor [Rattus norvegicus] >gb|AAI07672.1| Tumor necrosis factor (TNF superfamily, member 2) [Rattus norvegicus] >gb|AAK53568.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53569.1| tumor necrosis factor alpha [Rattus norvegicus] >gb|AAK53570.1| tumor necrosis factor alpha [Rattus norvegicus]
235 aa protein
accession:NP_036807.1
tumor necrosis factor isoform 1 [Mus musculus] >sp|P06804.2| RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor [Mus musculus] >gb|AAA18594.1| tumor necrosis factor [Mus musculus] >gb|AAA40458.1| tumor necrosis factor precursor [Mus musculus] >gb|AAA40459.1| tumor necrosis factor [Mus musculus] >gb|AAC82484.1| TNF [Mus musculus] >gb|AAI17058.1| Tumor necrosis factor [Mus musculus]
235 aa protein
accession:NP_038721.1
tumor necrosis factor isoform 2 [Mus musculus] >gb|AAA40462.1| tumor necrosis factor [Mus musculus] >gb|EDL26631.1| tumor necrosis factor, isoform CRA_a [Mus musculus]
219 aa protein
accession:NP_001265530.1
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Query sequence
nr matches
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Gap
Descriptions
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Available columns
| Select for downloading or viewing reports | Description | Max score | Total score | Query cover | E value | Ident | Accession |
|---|---|---|---|---|---|---|---|
| 1 | 437 | 437 | 100% | 1e-156 | 94.47% | NP_038721.1 | |
| 2 | 374 | 374 | 100% | 7e-132 | 78.39% | NP_000585.2 | |
| 3 | 94.4 | 94.4 | 67% | 3e-22 | 33.53% | NP_998024.2 | |
| 4 | 392 | 392 | 100% | 2e-139 | 87.23% | NP_001265530.1 | |
| 5 | 97.8 | 97.8 | 62% | 9e-24 | 39.07% | NP_034865.1 |