Summary [?]
A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query:
P42575.2
RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor
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Query length:
452 aa
DOMAINS: and other(s) domains
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Cell death protein 3 subunit p17 tein 3 subunit p17 [Caenorhabditis elegans]
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Cell death protein 3 subunit p17 [Caenorhabditis elegans] >emb|CBK19388.1| Cell death protein 3 subunit p17 [Caenorhabditis elegans]
287 aa protein
accession:NP_001255709.1
caspase-2 009290451.1| caspase-2 isoform X2 [Danio rerio] >gb|AAI63115.1| Caspase 2, apoptosis-related cysteine protease [Danio rerio] >gb|AAI63139.1| Caspase 2, apoptosis-related cysteine protease [Danio rerio] >gb|ABG91569.1| caspase 2 [Danio rerio]
...
caspase-2 [Danio rerio] >ref|XP_009290451.1| caspase-2 isoform X2 [Danio rerio] >gb|AAI63115.1| Caspase 2, apoptosis-related cysteine protease [Danio rerio] >gb|AAI63139.1| Caspase 2, apoptosis-related cysteine protease [Danio rerio] >gb|ABG91569.1| caspase 2 [Danio rerio]
435 aa protein
accession:NP_001036160.1
Query: RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor
...
RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor
452 aa protein
accession:P42575.2
caspase-2 isoform 1 precursor Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor [Mus musculus] >emb|SJL87491.1| unnamed protein product, partial [Mammalian expression vector pCMF2E-mCASP-2] >emb|SJL87958.1| unnamed protein product [Yeast expression vector pGAD-mCASP-2] >emb|SJL88099.1| unnamed protein product [Mammalian expression vector pCAGGS-mCASP-2] >emb|SJL88363.1| unnamed protein product [Mammalian expression vector pCAGGS-mCASP-2a] >emb|SJL88381.1| unnamed protein product [Vector pGEM-mCASP-2] >dbj|BAA25876.1| caspase-2 [Mus musculus domesticus]
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caspase-2 isoform 1 precursor [Mus musculus] >sp|P29594.5| RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor [Mus musculus] >emb|SJL87491.1| unnamed protein product, partial [Mammalian expression vector pCMF2E-mCASP-2] >emb|SJL87958.1| unnamed protein product [Yeast expression vector pGAD-mCASP-2] >emb|SJL88099.1| unnamed protein product [Mammalian expression vector pCAGGS-mCASP-2] >emb|SJL88363.1| unnamed protein product [Mammalian expression vector pCAGGS-mCASP-2a] >emb|SJL88381.1| unnamed protein product [Vector pGEM-mCASP-2] >dbj|BAA25876.1| caspase-2 [Mus musculus domesticus]
452 aa protein
accession:NP_031636.1
caspase-2 isoform 2
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caspase-2 isoform 2 [Mus musculus]
267 aa protein
accession:NP_001396468.1
caspase-2 isoform 2 osis regulator ICH-1, suppressive form S - human [Homo sapiens] >gb|AAX36439.1| caspase 2 [synthetic construct] >gb|AAA58960.1| ICH-1S [Homo sapiens] >gb|AAP22347.1| unknown [Homo sapiens] >gb|AAX41639.1| caspase 2 [synthetic construct] >gb|EAW51860.1| hCG20684, isoform CRA_a [Homo sapiens]
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caspase-2 isoform 2 [Homo sapiens] >pir|B54821| apoptosis regulator ICH-1, suppressive form S - human [Homo sapiens] >gb|AAX36439.1| caspase 2 [synthetic construct] >gb|AAA58960.1| ICH-1S [Homo sapiens] >gb|AAP22347.1| unknown [Homo sapiens] >gb|AAX41639.1| caspase 2 [synthetic construct] >gb|EAW51860.1| hCG20684, isoform CRA_a [Homo sapiens]
312 aa protein
accession:NP_001215.1
DOMAINS: and other(s) domains
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Cell death protein 3 subunit p17 [Caenorhabditis elegans] >emb|CBK19388.1| Cell death protein 3 subunit p17 [Caenorhabditis elegans]
287 aa protein
accession:NP_001255709.1
caspase-2 [Danio rerio] >ref|XP_009290451.1| caspase-2 isoform X2 [Danio rerio] >gb|AAI63115.1| Caspase 2, apoptosis-related cysteine protease [Danio rerio] >gb|AAI63139.1| Caspase 2, apoptosis-related cysteine protease [Danio rerio] >gb|ABG91569.1| caspase 2 [Danio rerio]
435 aa protein
accession:NP_001036160.1
RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor
452 aa protein
accession:P42575.2
caspase-2 isoform 1 precursor [Mus musculus] >sp|P29594.5| RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor [Mus musculus] >emb|SJL87491.1| unnamed protein product, partial [Mammalian expression vector pCMF2E-mCASP-2] >emb|SJL87958.1| unnamed protein product [Yeast expression vector pGAD-mCASP-2] >emb|SJL88099.1| unnamed protein product [Mammalian expression vector pCAGGS-mCASP-2] >emb|SJL88363.1| unnamed protein product [Mammalian expression vector pCAGGS-mCASP-2a] >emb|SJL88381.1| unnamed protein product [Vector pGEM-mCASP-2] >dbj|BAA25876.1| caspase-2 [Mus musculus domesticus]
452 aa protein
accession:NP_031636.1
caspase-2 isoform 2 [Mus musculus]
267 aa protein
accession:NP_001396468.1
caspase-2 isoform 2 [Homo sapiens] >pir|B54821| apoptosis regulator ICH-1, suppressive form S - human [Homo sapiens] >gb|AAX36439.1| caspase 2 [synthetic construct] >gb|AAA58960.1| ICH-1S [Homo sapiens] >gb|AAP22347.1| unknown [Homo sapiens] >gb|AAX41639.1| caspase 2 [synthetic construct] >gb|EAW51860.1| hCG20684, isoform CRA_a [Homo sapiens]
312 aa protein
accession:NP_001215.1
See full multiple alignment
Legend
Query sequence
nr matches
Landmark matches
Not aligned to query
Gap
Descriptions
Best hits
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Selected:0
Alignments
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GenPept
Graphics
Distance tree of results
Multiple alignment
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Available columns
| Select for downloading or viewing reports | Description | Max score | Total score | Query cover | E value | Ident | Accession |
|---|---|---|---|---|---|---|---|
| 1 | 812 | 812 | 100% | 0.0 | 89.60% | NP_031636.1 | |
| 2 | 596 | 596 | 64% | 0.0 | 100.00% | NP_001215.1 | |
| 3 | 400 | 400 | 94% | 1e-135 | 49.21% | NP_001036160.1 | |
| 4 | 150 | 150 | 56% | 7e-41 | 33.46% | NP_001255709.1 | |
| 5 | 409 | 409 | 55% | 9e-142 | 85.32% | NP_001396468.1 |