Summary [?]
A concise summary of the five best matches from well-studied reference species, showing phylogenetic relationships based on multiple sequence alignment and conserved protein domains. Additionally, more matches from the the non-redundant BLAST databases are included as "Additional BLAST Hits".
Query:
NP_061137.1
sphingomyelin phosphodiesterase 3 [Homo sapiens] >ref|XP_005256089.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_011521509.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_016878895.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290292.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290293.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290294.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290295.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290296.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290297.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169385.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169386.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169387.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169388.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169389.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169390.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169391.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169392.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169393.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >sp|Q9NY59.1| RecName: Full=Sphingomyelin phosphodiesterase 3; AltName: Full=Neutral sphingomyelinase 2; Short=nSMase-2; Short=nSMase2; AltName: Full=Neutral sphingomyelinase II [Homo sapiens] >gb|ADR83107.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II), partial [synthetic construct] >emb|SJX44036.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI12239.1| Sphingomyelin phosphodiesterase 3, neutral membrane [Homo sapiens] >gb|AIC51789.1| SMPD3, partial [synthetic construct] >gb|EAW83233.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) [Homo sapiens]
...
Query length:
655 aa
DOMAINS: and other(s) domains
...
endonuclease/exonuclease/phosphatase domain-containing protein 682 [Dictyostelium discoideum] >gb|EAS66955.1| endonuclease/exonuclease/phosphatase domain-containing protein [Dictyostelium discoideum AX4]
...
endonuclease/exonuclease/phosphatase domain-containing protein [Dictyostelium discoideum AX4] >sp|Q86IG2.1| RecName: Full=Uncharacterized protein DDB_G0272682 [Dictyostelium discoideum] >gb|EAS66955.1| endonuclease/exonuclease/phosphatase domain-containing protein [Dictyostelium discoideum AX4]
1107 aa protein
accession:XP_001134621.1
sphingomyelin phosphodiesterase 5 o rerio] >gb|AAI65400.1| Zgc:153995 protein [Danio rerio]
...
sphingomyelin phosphodiesterase 5 [Danio rerio] >gb|AAI24789.1| Zgc:153995 [Danio rerio] >gb|AAI65400.1| Zgc:153995 protein [Danio rerio]
545 aa protein
accession:NP_001071083.1
sphingomyelin phosphodiesterase 3 in phosphodiesterase 3 isoform X1 [Danio rerio] >dbj|BAG12870.1| neutral sphingomyelinase 2 [Danio rerio]
...
sphingomyelin phosphodiesterase 3 [Danio rerio] >ref|XP_005163129.1| sphingomyelin phosphodiesterase 3 isoform X1 [Danio rerio] >dbj|BAG12870.1| neutral sphingomyelinase 2 [Danio rerio]
684 aa protein
accession:NP_001116222.1
sphingomyelin phosphodiesterase 3 in phosphodiesterase 3 isoform X1 [Mus musculus] >ref|XP_011246764.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >ref|XP_011246765.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >sp|Q9JJY3.1| RecName: Full=Sphingomyelin phosphodiesterase 3; AltName: Full=Neutral sphingomyelinase 2; Short=nSMase-2; Short=nSMase2; AltName: Full=Neutral sphingomyelinase II [Mus musculus] >gb|AAH43077.1| Sphingomyelin phosphodiesterase 3, neutral [Mus musculus] >gb|AAH46980.1| Smpd3 protein [Mus musculus] >gb|EDL11359.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus] >gb|EDL11360.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus] >gb|EDL11361.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus]
...
sphingomyelin phosphodiesterase 3 [Mus musculus] >ref|XP_006531304.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >ref|XP_011246764.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >ref|XP_011246765.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >sp|Q9JJY3.1| RecName: Full=Sphingomyelin phosphodiesterase 3; AltName: Full=Neutral sphingomyelinase 2; Short=nSMase-2; Short=nSMase2; AltName: Full=Neutral sphingomyelinase II [Mus musculus] >gb|AAH43077.1| Sphingomyelin phosphodiesterase 3, neutral [Mus musculus] >gb|AAH46980.1| Smpd3 protein [Mus musculus] >gb|EDL11359.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus] >gb|EDL11360.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus] >gb|EDL11361.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus]
655 aa protein
accession:NP_067466.1
Query: sphingomyelin phosphodiesterase 3 in phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_011521509.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_016878895.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290292.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290293.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290294.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290295.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290296.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290297.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169385.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169386.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169387.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169388.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169389.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169390.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169391.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169392.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169393.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >sp|Q9NY59.1| RecName: Full=Sphingomyelin phosphodiesterase 3; AltName: Full=Neutral sphingomyelinase 2; Short=nSMase-2; Short=nSMase2; AltName: Full=Neutral sphingomyelinase II [Homo sapiens] >gb|ADR83107.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II), partial [synthetic construct] >emb|SJX44036.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI12239.1| Sphingomyelin phosphodiesterase 3, neutral membrane [Homo sapiens] >gb|AIC51789.1| SMPD3, partial [synthetic construct] >gb|EAW83233.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) [Homo sapiens]
...
sphingomyelin phosphodiesterase 3 [Homo sapiens] >ref|XP_005256089.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_011521509.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_016878895.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290292.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290293.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290294.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290295.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290296.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290297.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169385.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169386.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169387.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169388.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169389.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169390.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169391.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169392.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169393.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >sp|Q9NY59.1| RecName: Full=Sphingomyelin phosphodiesterase 3; AltName: Full=Neutral sphingomyelinase 2; Short=nSMase-2; Short=nSMase2; AltName: Full=Neutral sphingomyelinase II [Homo sapiens] >gb|ADR83107.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II), partial [synthetic construct] >emb|SJX44036.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI12239.1| Sphingomyelin phosphodiesterase 3, neutral membrane [Homo sapiens] >gb|AIC51789.1| SMPD3, partial [synthetic construct] >gb|EAW83233.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) [Homo sapiens]
655 aa protein
accession:NP_061137.1
sphingomyelin phosphodiesterase 3 isoform X2
...
sphingomyelin phosphodiesterase 3 isoform X2 [Homo sapiens]
476 aa protein
accession:XP_011521512.1
DOMAINS: and other(s) domains
...
endonuclease/exonuclease/phosphatase domain-containing protein [Dictyostelium discoideum AX4] >sp|Q86IG2.1| RecName: Full=Uncharacterized protein DDB_G0272682 [Dictyostelium discoideum] >gb|EAS66955.1| endonuclease/exonuclease/phosphatase domain-containing protein [Dictyostelium discoideum AX4]
1107 aa protein
accession:XP_001134621.1
sphingomyelin phosphodiesterase 5 [Danio rerio] >gb|AAI24789.1| Zgc:153995 [Danio rerio] >gb|AAI65400.1| Zgc:153995 protein [Danio rerio]
545 aa protein
accession:NP_001071083.1
sphingomyelin phosphodiesterase 3 [Danio rerio] >ref|XP_005163129.1| sphingomyelin phosphodiesterase 3 isoform X1 [Danio rerio] >dbj|BAG12870.1| neutral sphingomyelinase 2 [Danio rerio]
684 aa protein
accession:NP_001116222.1
sphingomyelin phosphodiesterase 3 [Mus musculus] >ref|XP_006531304.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >ref|XP_011246764.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >ref|XP_011246765.1| sphingomyelin phosphodiesterase 3 isoform X1 [Mus musculus] >sp|Q9JJY3.1| RecName: Full=Sphingomyelin phosphodiesterase 3; AltName: Full=Neutral sphingomyelinase 2; Short=nSMase-2; Short=nSMase2; AltName: Full=Neutral sphingomyelinase II [Mus musculus] >gb|AAH43077.1| Sphingomyelin phosphodiesterase 3, neutral [Mus musculus] >gb|AAH46980.1| Smpd3 protein [Mus musculus] >gb|EDL11359.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus] >gb|EDL11360.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus] >gb|EDL11361.1| sphingomyelin phosphodiesterase 3, neutral, isoform CRA_a [Mus musculus]
655 aa protein
accession:NP_067466.1
sphingomyelin phosphodiesterase 3 [Homo sapiens] >ref|XP_005256089.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_011521509.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_016878895.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290292.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290293.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290294.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290295.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290296.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_047290297.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169385.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169386.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169387.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169388.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169389.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169390.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169391.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169392.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >ref|XP_054169393.1| sphingomyelin phosphodiesterase 3 isoform X1 [Homo sapiens] >sp|Q9NY59.1| RecName: Full=Sphingomyelin phosphodiesterase 3; AltName: Full=Neutral sphingomyelinase 2; Short=nSMase-2; Short=nSMase2; AltName: Full=Neutral sphingomyelinase II [Homo sapiens] >gb|ADR83107.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II), partial [synthetic construct] >emb|SJX44036.1| unnamed protein product, partial [Human ORFeome Gateway entry vector] >gb|AAI12239.1| Sphingomyelin phosphodiesterase 3, neutral membrane [Homo sapiens] >gb|AIC51789.1| SMPD3, partial [synthetic construct] >gb|EAW83233.1| sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) [Homo sapiens]
655 aa protein
accession:NP_061137.1
sphingomyelin phosphodiesterase 3 isoform X2 [Homo sapiens]
476 aa protein
accession:XP_011521512.1
See full multiple alignment
Legend
Query sequence
nr matches
Landmark matches
Not aligned to query
Gap
Descriptions
Best hits
Show all columns of the table presenting best hits producing significant alignments
Select:AllNone
Selected:0
Alignments
Download
GenPept
Graphics
Distance tree of results
Multiple alignment
Show/hide columns of the table presenting best hits
Available columns
| Select for downloading or viewing reports | Description | Max score | Total score | Query cover | E value | Ident | Accession |
|---|---|---|---|---|---|---|---|
| 1 | 1233 | 1233 | 100% | 0.0 | 91.02% | NP_067466.1 | |
| 2 | 906 | 906 | 72% | 0.0 | 94.49% | XP_011521512.1 | |
| 3 | 698 | 698 | 100% | 0.0 | 55.19% | NP_001116222.1 | |
| 4 | 46.6 | 46.6 | 24% | 9e-04 | 24.72% | XP_001134621.1 | |
| 5 | 316 | 478 | 77% | 9e-99 | 50.47% | NP_001071083.1 |