ElasticBLAST (version 1.2.0) is a cloud-based tool to perform your BLAST searches faster and make you more effective.

ElasticBLAST is ideal for users who have a large number (thousands or more) of queries to BLAST or who prefer to use cloud infrastructure for their searches. It can run BLAST searches that cannot be done on NCBI WebBLAST and runs them more quickly than stand-alone BLAST+.

ElasticBLAST speeds up your work by distributing your searches across multiple cloud instances. The ability to scale resources in this way allows large numbers of queries to be searched in a shorter time that you normally could with BLAST+.

The National Center for Biotechnology Information (NCBI), part of the National Library of Medicine at the NIH, develops and maintains ElasticBLAST.

ElasticBLAST status: beta

Platforms available: AWS, GCP (account required)

Getting started: Go to the Overview or try out a quick-start (Quickstart for GCP, Quickstart for AWS) and then explore the demos.

Citing ElasticBLAST:

Camacho C, Boratyn GM, Joukov V, Vera Alvarez R, Madden TL. ElasticBLAST: accelerating sequence search via cloud computing. BMC Bioinformatics. 2023 Mar 26;24(1):117. doi: 10.1186/s12859-023-05245-9. PMID: 36967390;